Casp3

Gene Symbol	Casp3
Entrez Gene	12367
Alt Symbol	A830040C14Rik, AC-3, Apopain, CASP-3, CC3, CPP-32, CPP32, Caspase-3, Lice, SCA-1, Yama, mldy
Species	Mouse
Gene Type	protein-coding
Description	caspase 3
Other Description	SREBP cleavage activity 1|caspase 3, apoptosis related cysteine protease|caspase-3|cysteine protease CPP32|protein Yama
Swissprots	O08668 Q8CHV5 Q9QWI4 P70677
Accessions	AAC52768 EDL35577 EDL35578 EDL35579 EDL35580 EDL35581 EDL35582 P70677 AK014231 AK049043 AK080651 BAC37969 AK146226 BC021500 BC038825 AAH38825 D86352 BAA21727 U19522 AAC53196 U49929 AAC52764 U63720 AAD09504 Y13086 CAA73528 NM_001284409 NP_001271338 NM_009810 NP_033940
Function	Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop- helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Triggers cell adhesion in sympathetic neurons through RET cleavage (By similarity). Cleaves IL-1 beta between an Asp and an Ala, releasing the mature cytokine which is involved in a variety of inflammatory processes. {ECO:0000250}.
Subcellular Location	Cytoplasm.
Tissue Specificity	Highest expression in spleen, lung, liver, kidney and heart. Lower expression in brain, skeletal muscle and testis.
Top Pathways	Toxoplasmosis, TNF signaling pathway, MicroRNAs in cancer, Non-alcoholic fatty liver disease (NAFLD), Proteoglycans in cancer

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones

Caspase-3 Protein - NBP1-99208 from Novus Biologicals Category Protein Species Mouse

Caspase-3 Protein - NBP1-99922 from Novus Biologicals Category Protein Prices $469.00 Sizes 5 µg Species Mouse

Caspase-3 Protein - NBP1-99593 from Novus Biologicals Category Protein Prices $429.00 Sizes 100 tests Species Mouse

Caspase-3 Recombinant Protein - P4486 from Novus Biologicals Category Protein Prices $919.00 Sizes 5 µg Species Mouse

mouse-CASP3-Antibody-N-term-S12-Blocking-Peptide - BP18708a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg Species Mouse

mouse-CASP3-Antibody-N-term-S26-Blocking-Peptide - BP18707a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg Species Mouse

Phospho-mouse-CASP3S26-Antibody-Blocking-peptide - BP3778d from Abgent, a WuXi AppTec company Category Peptide Prices $120.00 Sizes 100 µg Species Mouse

Phospho-mouse-CASP3S12-Antibody-Blocking-peptide - BP3778b from Abgent, a WuXi AppTec company Category Peptide Prices $120.00 Sizes 100 µg Species Mouse

Recombinant human Caspase-3 (OPCA00589) - OPCA00589 from Aviva Systems Biology Category Protein Prices $198.00 Sizes 50 µg Species Human

Mouse Caspase 3 Protein - abx065759 from Abbexa Category Protein Source E.coli Species Mouse

Caspase-3 - P4485 from Acris Antibodies Category Protein Prices $430.00 Sizes 25 u Species Mouse

Caspase-3 - P4486 from Acris Antibodies Category Protein Prices $750.00 Sizes 5 µg Species Mouse

Caspase 3 (CASP3), Mouse - 20-6905 from ARP American Research Products Category Protein Prices $529.00 Sizes 50 µg Source E.coli Species Mouse

Recombinant Mouse Caspase 3 - Casp3-1643M from Creative Biomart Category Protein Source E. coli Species Human

Recombinant Mouse Caspase 3 - Casp3-1641M from Creative Biomart Category Protein Source E. coli Species Human

Recombinant Caspase 3 (CASP3) - RPA626Mu01 from Cloud-clone Category Protein Source E.coli Species Mouse

Recombinant Caspase 3 (CASP3) - RPA626Mu02 from Cloud-clone Category Protein Source E.coli Species Mouse

Recombinant Mouse Caspase-3(Casp3) - CSB-YP004548MO CSB-EP004548MO CSB-BP004548MO CSB-MP004548MO from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Mouse

Caspase-3 Proform, mouse recombinant - 1183P-5 from Biovision Category Protein Prices $325.00 Sizes 5 µg Source E. coli Species Mouse

Caspase-3, mouse recombinant - 1183-100 from Biovision Category Protein Prices $285.00 Sizes 100 units Source E. coli Species Mouse

Caspase-3, mouse recombinant - 1183-25 from Biovision Category Protein Prices $145.00 Sizes 25 units Source E. coli Species Mouse

Caspase 3 (CASP3) - RPU140668 from Biomatik Category Protein Prices $253.00, $506.00, $759.00 Sizes 10 µg, 50 µg, 100 µg Source E.coli Species Mouse

Caspase 3 (CASP3), Recombinant Protein - MBS2009683 from MyBioSource Category Protein Prices $195.00, $410.00, $635.00 Sizes 10 µg, 50 µg, 100 µg Source Prokaryotic expression Species Mouse

Caspase-3 (Casp3), Recombinant Protein - MBS949200 from MyBioSource Category Protein Prices $885.00, $885.00, $1,110.00, $1,110.00, $1,300.00, $1,300.00, $1,755.00, $1,755.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Mouse

Recombinant Mouse CASP3 Protein - CASP3-2752M from Creative Biomart Category Protein Source Mammalian Cells Species Mouse

Search more