Casp3

Gene Symbol	Casp3
Entrez Gene	12367
Alt Symbol	A830040C14Rik, AC-3, Apopain, CASP-3, CC3, CPP-32, CPP32, Caspase-3, Lice, SCA-1, Yama, mldy
Species	Mouse
Gene Type	protein-coding
Description	caspase 3
Other Description	SREBP cleavage activity 1|caspase 3, apoptosis related cysteine protease|caspase-3|cysteine protease CPP32|protein Yama
Swissprots	O08668 Q8CHV5 Q9QWI4 P70677
Accessions	AAC52768 EDL35577 EDL35578 EDL35579 EDL35580 EDL35581 EDL35582 P70677 AK014231 AK049043 AK080651 BAC37969 AK146226 BC021500 BC038825 AAH38825 D86352 BAA21727 U19522 AAC53196 U49929 AAC52764 U63720 AAD09504 Y13086 CAA73528 NM_001284409 NP_001271338 NM_009810 NP_033940
Function	Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop- helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Triggers cell adhesion in sympathetic neurons through RET cleavage (By similarity). Cleaves IL-1 beta between an Asp and an Ala, releasing the mature cytokine which is involved in a variety of inflammatory processes. {ECO:0000250}.
Subcellular Location	Cytoplasm.
Tissue Specificity	Highest expression in spleen, lung, liver, kidney and heart. Lower expression in brain, skeletal muscle and testis.
Top Pathways	Toxoplasmosis, TNF signaling pathway, MicroRNAs in cancer, Non-alcoholic fatty liver disease (NAFLD), Proteoglycans in cancer

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones

Active caspase-3, Mouse, ELISA Kit - E03A0015 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t Sensitivity 0.1ng/ml Range 1.0-25ng/ml

Caspase 3 (CASP3), Mouse, ELISA Kit - SEA626Mu from ARP American Research Products Category ELISA Kit Prices $668.00 Sizes 96 t Sensitivity 0.255ng/mL Range 0.625-40ng/mL

Caspase 3, Casp-3, Mouse, ELISA Kit - CSB-E08858m from ARP American Research Products Category ELISA Kit Prices $465.00, $615.00, $616.00, $619.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t

Caspase 3, Mouse, ELISA Kit - E03C0549 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t Sensitivity 0.1ng/ml Range 0.5-10ng/mL,

Caspase-3, Casp3, Mouse, ELISA Kit - E0626m from ARP American Research Products Category ELISA Kit Prices $496.00 Sizes 96 t Range 0.156-10 ng/mL

Caspase-3, Mouse, ELISA Kit - E03C0094 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t Sensitivity 0.1ng/ml Range 0.5-10ng/mL

Cysteinyl Aspartate Specific Proteinases 3, Caspase-3/CPP32, Mouse, ELISA Kit - YHB0383Mo from ARP American Research Products Category ELISA Kit

Mouse Caspase-3 ELISA Kit - MC0556 from NeoScientific Category ELISA Kit Prices $495.00 Sizes 96 t

Mouse Caspase-3/CPP32 ELISA Kit - MC0698 from NeoScientific Category ELISA Kit Prices $495.00 Sizes 96 t

Mouse CASP3(Caspase 3) ELISA Kit - E-EL-M0238 from Elabscience Category ELISA Kit Sensitivity 0.10 ng/mL Range 0.16—10 ng/mL

Mouse CASP3 (Caspase 3) CLIA Kit - E-CL-M0173 from Elabscience Category CLIA Kit Sensitivity 18.75 pg/mL Range Average Recovery (%)

Active caspase-3, ELISA Kit - MBS7210856 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.1 ng/mL

caspase 3, apoptosis-related cysteine peptidase, ELISA Kit - MBS702352 from MyBioSource Category ELISA Kit Prices $250.00, $450.00, $640.00, $2,615.00, $4,940.00 Sizes 24 -strip-wells (Limit 1), 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.078 ng/ml. Range 0.312 ng/ml -20 ng/ml.

Caspase-3/CPP32, ELISA Kit - MBS9300879 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

cysteinyl aspartate specific proteinases 3, Caspase-3/CPP32, ELISA Kit - MBS9300583 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

cysteinyl aspartate specific proteinases 3, Caspase-3/CPP32, ELISA Kit - MBS9304051 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Mouse Caspase 3,Casp-3 ELISA Kit - CSB-E08858m from Cusabio Category ELISA Kit Sensitivity 0.078ng/ml Range 0.312 ng/ml-20 ng/ml

Mouse Caspase 3 ELISA - E03C0549 from BlueGene Biotech Category ELISA Kit Sensitivity 0.1 ng/mL

ELISA Kit for Caspase 3 (CASP3) - SEA626Mu from Cloud-clone Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.244ng/mL. Range 0.625-40ng/mL The standard curve concentrations used for the ELISA's were 40ng/mL, 20ng/mL, 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL

Mouse Caspase 3 (CASP3) ELISA Kit - EKU02990 from Biomatik Category ELISA Kit Prices $680.00, $3,028.00, $5,511.00 Sizes 96 t, 5x96t, 10x96t Sensitivity 0.244 ng/mL Range 0.625-40 ng/mL

Mouse CASP3(Caspase 3) ELISA Kit - E-EL-M0238 from Iwai North America Inc. Category ELISA Kit Prices $580.00 Sizes 1 kit Sensitivity 0.1 ng/mL Range 0.16~10 ng/mL

Mouse CASP3 (Caspase 3) CLIA Kit - E-CL-M0173 from Iwai North America Inc. Category CLIA Kit Prices $722.50 Sizes 1 kit Sensitivity 0.094ng/mL Range 0.156-10ng/mL

Mouse MIP-3Alpha (Macrophage Inflammatory Protein 3 Alpha) CLIA Kit - E-CL-M0012 from Iwai North America Inc. Category CLIA Kit Prices $722.50 Sizes 1 kit Sensitivity 4.688pg/mL Range 7.813-500pg/mL

Mouse Caspase 3 ELISA Kit - abx153770 from Abbexa Category ELISA Kit Range 0.313 ng/ml - 20 ng/ml

Mouse Caspase-3 ELISA Kit - abx254635 from Abbexa Category ELISA Kit Range 0.156 ng/ml - 10 ng/ml

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