RAMP3

Gene Symbol	RAMP3
Entrez Gene	10268
Alt Symbol	-
Species	Human
Gene Type	protein-coding
Description	receptor (G protein-coupled) activity modifying protein 3
Other Description	CRLR activity-modifying protein 3|calcitonin receptor-like receptor activity modifying protein 3|calcitonin-receptor-like receptor activity-modifying protein 3|receptor (calcitonin) activity modifying protein 3|receptor activity modifying protein 3|receptor activity-modifying protein 3|receptor-activity-modifying protein 3
Swissprots	Q7Z2Y1 O60896
Accessions	BAN10197 BAN10198 EAL23743 EAW61048 EAW61049 EAW61050 O60896 AJ001016 CAA04474 AK128765 AK222469 BAD96189 AK311871 BAG34812 AY265459 AAP23300 BC022304 AAH22304 BC053852 AAH53852 BP347072 DQ891371 ABM82297 HQ448585 ADQ33063 XM_006715631 XP_006715694 NM_005856 NP_005847
Function	Plays a role in cardioprotection by reducing cardiac hypertrophy and perivascular fibrosis in a GPER1-dependent manner. Transports the calcitonin gene-related peptide type 1 receptor (CALCRL) and GPER1 to the plasma membrane. Acts as a receptor for adrenomedullin (AM) together with CALCRL. {ECO:0000269|PubMed:23674134, ECO:0000269|PubMed:9620797}.
Subcellular Location	Cell membrane {ECO:0000269|PubMed:23674134}; Single-pass type I membrane protein {ECO:0000269|PubMed:23674134}. Membrane {ECO:0000269|PubMed:23674134}; Single-pass type I membrane protein {ECO:0000269|PubMed:23674134}. Note=Moves from intracellular puncta to the plasma membrane in a RAMP3-dependent manner.
Tissue Specificity	Strongly expressed in lung, breast, immune system and fetal tissues. {ECO:0000269|PubMed:9620797}.
Top Pathways	Vascular smooth muscle contraction

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

RAMP3-Over-expression-Lysate - LY15577a from Abgent, a WuXi AppTec company Category Cell Lysate Prices $325.00 Sizes 100 µg

RAMP3 293 Cell Lysate - 407961 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg

RAMP3 Overexpression Lysate (Native) - NBL1-15138 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

RAMP3 (h): 293T Lysate - sc-116550 from Santa Cruz Biotechnology Category Cell Lysate Prices $205.00 Sizes 100 µg/200 µl Species Human

RAMP3 Over-expression Lysate Product - GWB-275350 from Genway Biotech Category Cell Lysate Prices $346.00 Sizes 100 µg Species Human

Human RAMP3 HEK293 Cell Lysate (WB positive control) - 13744-H02HL-300 from Sino Biological Category Cell Lysate Prices $195.00 Sizes 300 µg Species Human

Human RAMP3 Protein (Fc Tag) - 13744-H02H-100 13744-H02H-20 from Sino Biological Category Protein Prices $348.00, $348.00 Sizes 20 µg, 100 µg Species Human

Human RAMP3 Human Cells Transfected Lysate (positive control) (denatured) - orb174457 from Biorbyt Category Cell Lysate Prices $425.00 Sizes 300 μg Species Human

RAMP3 Overexpression Lysate (Denatured) - H00010268-T01 from Novus Biologicals Category Cell Lysate Prices $279.00 Sizes 100 µl

Human RAMP3 Protein (Fc Tag) - 13744-H02H-100 from Sino Biological Category Protein Species Human

Panoply™ Human RAMP3 Knockdown Stable Cell Line - CSC-DC012947 from Creative biogene Category Cell Line Species Human

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