Gene Symbol | CD80 |
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Entrez Gene | 941 |
Alt Symbol | B7, B7-1, B7.1, BB1, CD28LG, CD28LG1, LAB7 |
Species | Human |
Gene Type | protein-coding |
Description | CD80 molecule |
Other Description | B-lymphocyte activation antigen B7|CD80 antigen (CD28 antigen ligand 1, B7-1 antigen)|CTLA-4 counter-receptor B7.1|T-lymphocyte activation antigen CD80|activation B7-1 antigen|costimulatory factor CD80|costimulatory molecule variant IgV-CD80 |
Swissprots | P33681 Q5DTB0 Q5DTA9 |
Accessions | AAA58390 AAC51754 ABK41933 EAW79564 EAW79565 P33681 AK292129 BAF84818 AY081815 AAL89819 AY197777 AAO39208 AY197778 AAO39209 BC042665 AAH42665 BP225173 M27533 AAA36045 XM_011513325 XP_011511627 XM_011513326 XP_011511628 XM_011513327 XP_011511629 NM_005191 NP_005182 |
Function | Involved in the costimulatory signal essential for T- lymphocyte activation. T-cell proliferation and cytokine production is induced by the binding of CD28, binding to CTLA-4 has opposite effects and inhibits T-cell activation. {ECO:0000269|PubMed:10583602}. |
Subcellular Location | Membrane; Single-pass type I membrane protein. |
Tissue Specificity | Expressed on activated B-cells, macrophages and dendritic cells. |
Top Pathways | Toll-like receptor signaling pathway, Type I diabetes mellitus, Graft-versus-host disease, Allograft rejection, Autoimmune thyroid disease |
B7-1 (F-7) - sc-376012 from Santa Cruz Biotechnology
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B7-1 (C-20) - sc-1633 from Santa Cruz Biotechnology
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B7-1 (H-208) - sc-9091 from Santa Cruz Biotechnology
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B7-1 (N-20) - sc-1634 from Santa Cruz Biotechnology
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B7-1 (2D10) - sc-73382 from Santa Cruz Biotechnology
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Anti-CD80 antibody - ab104033 from Abcam
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Anti-CD80 antibody - ab106747 from Abcam
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Anti-CD80 antibody [2A2] - ab86473 from Abcam
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Anti-CD80 antibody [2D10.4], prediluted (PE/Cy5®) - ab155374 from Abcam
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Anti-CD80 antibody [2D10.4] - Low endotoxin, Azide free - ab185742 from Abcam
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Anti-CD80 antibody [EPR1157(2)] - ab134120 from Abcam
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Anti-CD80 antibody [MEM-233] - ab8239 from Abcam
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Anti-CD80 antibody [MEM-233] (Allophycocyanin) - ab27554 from Abcam
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Anti-CD80 antibody [MEM-233] (FITC) - ab18279 from Abcam
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Anti-CD80 antibody [MEM-233] (PerCP) - ab82410 from Abcam
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Anti-CD80 antibody [MEM-233], prediluted (Phycoerythrin) - ab69778 from Abcam
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Anti-CD80 Antibody - LS-C306857 from LifeSpan Bioscience
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Anti-CD80 Antibody (aa1-224) - LS-C311768 from LifeSpan Bioscience
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Anti-CD80 Antibody (aa258-288, FITC) - LS-C254133 from LifeSpan Bioscience
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Anti-CD80 Antibody - LS-C309833 from LifeSpan Bioscience
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Anti-CD80 Antibody (aa258-288) - LS-C320207 from LifeSpan Bioscience
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Anti-CD80 Antibody (clone 1G1) - LS-C196850 from LifeSpan Bioscience
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Anti-CD80 Antibody (clone 2E5) - LS-C115529 from LifeSpan Bioscience
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Anti-CD80 Antibody (aa227-245) - LS-C343886 from LifeSpan Bioscience
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Anti-CD80 Antibody (clone 3F1) - LS-C172390 from LifeSpan Bioscience
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