CD80

Gene Symbol	CD80
Entrez Gene	941
Alt Symbol	B7, B7-1, B7.1, BB1, CD28LG, CD28LG1, LAB7
Species	Human
Gene Type	protein-coding
Description	CD80 molecule
Other Description	B-lymphocyte activation antigen B7|CD80 antigen (CD28 antigen ligand 1, B7-1 antigen)|CTLA-4 counter-receptor B7.1|T-lymphocyte activation antigen CD80|activation B7-1 antigen|costimulatory factor CD80|costimulatory molecule variant IgV-CD80
Swissprots	P33681 Q5DTB0 Q5DTA9
Accessions	AAA58390 AAC51754 ABK41933 EAW79564 EAW79565 P33681 AK292129 BAF84818 AY081815 AAL89819 AY197777 AAO39208 AY197778 AAO39209 BC042665 AAH42665 BP225173 M27533 AAA36045 XM_011513325 XP_011511627 XM_011513326 XP_011511628 XM_011513327 XP_011511629 NM_005191 NP_005182
Function	Involved in the costimulatory signal essential for T- lymphocyte activation. T-cell proliferation and cytokine production is induced by the binding of CD28, binding to CTLA-4 has opposite effects and inhibits T-cell activation. {ECO:0000269|PubMed:10583602}.
Subcellular Location	Membrane; Single-pass type I membrane protein.
Tissue Specificity	Expressed on activated B-cells, macrophages and dendritic cells.
Top Pathways	Toll-like receptor signaling pathway, Type I diabetes mellitus, Graft-versus-host disease, Allograft rejection, Autoimmune thyroid disease

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Active human CD80 protein fragment - ab173993 from Abcam Category Protein Prices $314.00 Sizes 100 µg Source HEK 293 cells Species Human

Active human CD80 protein fragment - ab180050 from Abcam Category Protein Prices $314.00 Sizes 100 µg Source HEK 293 cells Species Human

Human CD80 full length protein - ab131745 from Abcam Category Protein Prices $402.00 Sizes 10 µg Source Wheat germ Species Human

Human CD80 full length protein - ab131746 from Abcam Category Protein Prices $402.00 Sizes 10 µg Source Wheat germ Species Human

Human CD80 protein fragment - ab198630 from Abcam Category Protein Prices $625.00 Sizes 100 µg Source HEK 293 cells Species Human

Human CD80 protein fragment - ab73007 from Abcam Category Protein Prices $235.00 Sizes 50 µg Species Human

Mouse CD80 peptide - ab66476 from Abcam Category Peptide

CD80 Antibody Blocking Peptide - LS-E7695 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

CD80 Antibody Blocking Peptide - LS-E27207 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

CD80 Antibody Blocking Peptide - LS-E22984 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Mouse B7-1/CD80 Protein - NBP2-26578 from Novus Biologicals Category Protein Prices $199.00 Sizes 50 µg

B7-1/CD80 Recombinant Protein - H00000941-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

B7-1/CD80 Recombinant Protein - H00000941-P03 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg

B7-1/CD80 Recombinant Protein - H00000941-G01 from Novus Biologicals Category Protein Prices $579.00 Sizes 10 µg Species Human

CD80-Antibody-C-term-Blocking-Peptide - BP5020b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

CD80 blocking peptide - GTX88300-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human

Recombinant Human B7-1/CD80 Fc Chimera, CF - 140-B1-100 from R&D Systems Category Protein Source Mouse myeloma cell line, NS0-derived

CD80 Peptide - AC21-2028-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

CD80 (Fc portion) - AR31192PU-N from Acris Antibodies Category Protein Prices $235.00 Sizes 100 µg Source CHO cells Species Human

CD80 (Fc portion) - AR31192PU-S from Acris Antibodies Category Protein Prices $135.00 Sizes 20 µg Source CHO cells Species Human

CD80 - H00000941-G01 from Acris Antibodies Category Protein Prices $550.00 Sizes 10 µg Species Human

CD80 - H00000941-H01 from Acris Antibodies Category Protein Prices $770.00 Sizes 25 µg Source Human HEK293T cells Species Human

CD80 - H00000941-H02 from Acris Antibodies Category Protein Prices $770.00 Sizes 25 µg Source Human HEK293T cells Species Human

CD80 - H00000941-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

CD80 - H00000941-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

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