THEMIS

Gene Symbol THEMIS
Entrez Gene 387357
Alt Symbol C6orf190, C6orf207, GASP, SPOT, TSEPA, bA325O24.3, bA325O24.4
Species Human
Gene Type protein-coding
Description thymocyte selection associated
Other Description GRB2-associated protein|protein THEMIS|signaling phosphoprotein specific for T cells|thymocyte expressed molecule involved in selection|thymocyte selection pathway associated|thymocyte-expressed molecule involved in selection
Swissprots Q5T3C4 Q8N1K5 Q6MZT7 F5H1J9 A1L4F0 B3KY07 Q5T3C5 A8K7N1 B3KT31 B3KW32
Accessions CAY56007 CBX47634 EAW48091 EAW48092 Q8N1K5 AK094863 BAG52943 AK097903 BAC05194 AK124031 BAG53994 AK128377 BAG54669 AK292046 BAF84735 BC043608 BC130516 AAI30517 BC144034 BG461112 BX640890 CAE45941 BX956657 DA818250 HQ258481 ADR83235 XM_011535813 XP_011534115 XM_011535814 XP_011534116 XM_011535815 XP_011534117 XM_011535816 XP_011534118 XM_011535817 XP_011534119 XM_011546483 XP_011544785 XM_011546484 XP_011544786 XM_011546485 XP_011544787 XM_011546486 XP_011544788 XM_011546487 XP_011544789 NM_001010923 NP_001010923 NM_001164685 NP_001158157 NM_001164687 NP_001158159
Function Plays a central role in late thymocyte development by controlling both positive and negative T-cell selection. Required to sustain and/or integrate signals required for proper lineage commitment and maturation of T-cells. Regulates T-cell development through T-cell antigen receptor (TCR) signaling and in particular through the regulation of calcium influx and phosphorylation of Erk (By similarity). {ECO:0000250}.
Subcellular Location Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}.

Themis CRISPR/Cas9 KO Plasmid (h) - sc-415743 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Themis HDR Plasmid (h) - sc-415743-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Themis Double Nickase Plasmid (h) - sc-415743-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Themis Double Nickase Plasmid (h2) - sc-415743-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Themis CRISPR Activation Plasmid (h) - sc-415743-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Themis CRISPR Activation Plasmid (h2) - sc-415743-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Themis Lentiviral Activation Particles (h) - sc-415743-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Themis Lentiviral Activation Particles (h2) - sc-415743-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Themis siRNA (h) - sc-95448 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Themis shRNA Plasmid (h) - sc-95448-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Themis shRNA (h) Lentiviral Particles - sc-95448-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU043771 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN21310 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND21310 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR13187 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr13187

THEMIS siRNA (Human) - CRJ7737 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

THEMIS - MBS8238098 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human THEMIS (NM_001010923.2) - SHH426860 from Creative biogene

Category siRNA
Species Reactivities Human

Human THEMIS siRNA - orb278238 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

THEMIS shRNA Plasmid (Human) - CHJ7737 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

THEMIS miRNA 3'UTR clone - MiUTR3H-12973 from Creative biogene

Species Reactivities Human

THEMIS miRNA 3'UTR clone - MiUTR3H-12974 from Creative biogene

Species Reactivities Human

THEMIS miRNA 3'UTR clone - MiUTR3H-12975 from Creative biogene

Species Reactivities Human
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