CCL19

Gene Symbol CCL19
Entrez Gene 6363
Alt Symbol CKb11, ELC, MIP-3b, MIP3B, SCYA19
Species Human
Gene Type protein-coding
Description chemokine (C-C motif) ligand 19
Other Description C-C motif chemokine 19|CC chemokine ligand 19|CK beta-11|EBI1 ligand chemokine|EBI1-ligand chemokine|MIP-3-beta|beta chemokine exodus-3|beta-chemokine exodus-3|epstein-Barr virus-induced molecule 1 ligand chemokine|exodus-3|macrophage inflammatory protein 3 beta|macrophage inflammatory protein 3-beta|small inducible cytokine subfamily A (Cys-Cys), member 19|small-inducible cytokine A19
Swissprots O00697 O00736 Q99731
Accessions ABK41949 CAA11307 EAW58416 Q99731 AB000887 BAA20383 AK311945 BAG34886 AX772806 CAE06252 BC027968 AAH27968 CR456868 CAG33149 DQ895236 ABM86162 EU176240 ABW03691 U77180 AAC50944 U88321 AAC23905 NM_006274 NP_006265
Function May play a role not only in inflammatory and immunological responses but also in normal lymphocyte recirculation and homing. May play an important role in trafficking of T-cells in thymus, and T-cell and B-cell migration to secondary lymphoid organs. Binds to chemokine receptor CCR7. Recombinant CCL19 shows potent chemotactic activity for T-cells and B-cells but not for granulocytes and monocytes. Binds to atypical chemokine receptor ACKR4 and mediates the recruitment of beta-arrestin (ARRB1/2) to ACKR4. {ECO:0000269|PubMed:9498785}.
Subcellular Location Secreted.
Tissue Specificity Expressed at high levels in the lymph nodes, thymus and appendix. Intermediate levels seen in colon and trachea, while low levels found in spleen, small intestine, lung, kidney and stomach.
Top Pathways Cytokine-cytokine receptor interaction, Chemokine signaling pathway

Active Macrophage Inflammatory Protein 3 beta full length protein - ab9832 from Abcam

Category Protein
Prices $110.00, $239.00
Sizes 5 µg, 20 µg
Source E. coli

Active mouse Macrophage Inflammatory Protein 3 beta full length protein - ab168015 from Abcam

Category Protein
Prices $883.00
Sizes 100 µg
Source E. coli
Species Mouse

Active mouse Macrophage Inflammatory Protein 3 beta full length protein - ab191713 from Abcam

Category Protein
Prices $192.00
Sizes 20 µg
Source E. coli
Species Mouse

Human Macrophage Inflammatory Protein 3 beta full length protein - ab97899 from Abcam

Category Protein
Source E. coli
Species Human
15% SDS-PAGE showing ab97899 at approximately 10.4kDa (3µg).

Human Macrophage Inflammatory Protein 3 beta full length protein - ab175155 from Abcam

Category Protein
Source Synthetic
Species Human

Human Macrophage Inflammatory Protein 3 beta full length protein - ab176065 from Abcam

Category Protein
Source Synthetic
Species Human

Mouse Macrophage Inflammatory Protein 3 beta full length protein - ab50169 from Abcam

Category Protein
Source E. coli
Species Mouse

CCL19/MIP-3 beta Recombinant Protein - H00006363-P02 from Novus Biologicals

Category Protein
Prices $369.00
Sizes 2 µg
Species Human

CCL19/MIP-3 beta Recombinant Protein - H00006363-P01 from Novus Biologicals

Category Protein
Prices $369.00
Sizes 2 µg
Species Human

CCL19/MIP-3 beta Protein - NBP1-44466 from Novus Biologicals

Category Protein
Prices $279.00
Sizes 100 µg
Species Human
SDS-Page: Macrophage Inflammatory Protein 3 beta Protein [NBP1-44466] - CCL19, 10.4 kDa (93aa) confirmed by MALDI-TOF with a purity of 95% by SDS - PAGE

CCL19/MIP-3 beta Recombinant Protein - P4430 from Novus Biologicals

Category Protein
Prices $549.00
Sizes 20 µg
Species Human

Recombinant Human CCL19/MIP-3 beta Protein - NBP1-99403 from Novus Biologicals

Category Protein
Prices $190.00
Sizes 20 µg
Source E. coli
Species Human

CCL19 protein - GTX29832 from GeneTex

Category Protein
Prices $299.00
Sizes 20 μg
Species Human

CCL19 Recombinant Protein (Active) - GTX48367-PRO from GeneTex

Category Protein
Prices $299.00
Sizes 20 μg
Source E. coli
Species Human

CCL19 recombinant protein - GTX65247 from GeneTex

Category Protein
Prices $249.00
Sizes 20 μg
Source E. coli
Species Human

Recombinant Human CCL19/MIP-3 beta - 361-MI-025 from R&D Systems

Category Protein
Source E. coli-derived, Gly22-Ser98

Recombinant Human CCL19/MIP-3 beta, CF - 361-MI-025/CF from R&D Systems

Category Protein
Source E. coli-derived, Gly22-Ser98

Recombinant Mouse CCL19/MIP-3 beta - 440-M3-025 from R&D Systems

Category Protein
Source E. coli-derived, Gly26-Val107-Leu-Glu, with a substitution of Ser108LeuGlu

Recombinant Mouse CCL19/MIP-3 beta, CF - 440-M3-025/CF from R&D Systems

Category Protein
Source E. coli-derived, Gly26-Val107-Leu-Glu, with a substitution of Ser108LeuGlu

CCL19 Protein (OPCB00011) - OPCB00011 from Aviva Systems Biology

Category Protein
Prices $80.00
Sizes 2 µg

Biotinylated CCL19 Protein (OPCB00021) - OPCB00021 from Aviva Systems Biology

Category Protein
Prices $160.00
Sizes 2 µg

Human MIP-3b Protein (OPMA04653) - OPMA04653 from Aviva Systems Biology

Category Protein
Prices $265.00
Sizes 20 µg
Source E. coli
Species Human

MIP 3b Protein (OPPA00405) - OPPA00405 from Aviva Systems Biology

Category Protein
Prices $100.00
Sizes 5 µg
Source E. Coli

CCL23 Protein (OPPA02327) - OPPA02327 from Aviva Systems Biology

Category Protein
Prices $160.00
Sizes 20 µg
Source E. Coli

Recombinant MIP-3 beta / CCL19 (OPSD00071) - OPSD00071 from Aviva Systems Biology

Category Protein
Prices $105.00
Sizes 5 µg
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