| Gene Symbol | Tlr13 |
|---|---|
| Entrez Gene | 279572 |
| Alt Symbol | AI666735, Gm713 |
| Species | Mouse |
| Gene Type | protein-coding |
| Description | toll-like receptor 13 |
| Other Description | - |
| Swissprots | Q3TDS2 Q148Y7 Q6R5N8 |
| Accessions | EDL14060 Q6R5N8 AK155696 AK170044 BAE41528 AY510706 AAS37674 BC117913 AAI17914 BC117914 AAI17915 NM_205820 NP_991389 |
| Function | Component of innate and adaptive immunity that recognizes and binds 23S rRNA from bacteria. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Specifically binds the 5'-CGGAAAGACC-3' sequence on bacterial 23S rRNA, a sequence also bound by MLS group antibiotics (including erythromycin). May also recognize vesicular stomatitis virus; however, these data require additional evidences. {ECO:0000269|PubMed:21131352, ECO:0000269|PubMed:22821982, ECO:0000269|PubMed:22896636}. |
| Subcellular Location | Endosome membrane {ECO:0000269|PubMed:22896636}; Single-pass type I membrane protein {ECO:0000269|PubMed:22896636}. |
Mouse TLR13 peptide - ab60788 from Abcam
|
||||||
Recombinant Mouse Toll-like receptor 13(Tlr13) - CSB-YP757699MO CSB-EP757699MO CSB-BP757699MO CSB-MP757699MO from Cusabio
|
||||||
Recombinant Mouse TLR13 Protein - TLR13-16823M from Creative Biomart
|
||||||