CERS1

Gene Symbol CERS1
Entrez Gene 10715
Alt Symbol EPM8, LAG1, LASS1, UOG1
Species Human
Gene Type protein-coding
Description ceramide synthase 1
Other Description longevity assurance (LAG1, S. cerevisiae) homolog 1|longevity assurance gene 1 protein homolog 1|protein UOG-1|upstream of GDF1
Swissprots P27544
Accessions AAD16892 EAW84745 EAW84746 P27544 AI671814 AK293463 BAG56958 AL120193 BC032615 BC084582 AAH84582 BF343384 BM925585 BX453803 NM_001290265 NP_001277194 NM_021267 NP_067090 NM_198207 NP_937850
Function May be either a bona fide (dihydro)ceramide synthase or a modulator of its activity. When overexpressed in cells is involved in the production of sphingolipids containing mainly one fatty acid donor (N-linked stearoyl- (C18) ceramide) in a fumonisin B1-independent manner (By similarity). {ECO:0000250}.
Subcellular Location Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Top Pathways Sphingolipid signaling pathway, Sphingolipid metabolism

LASS1 (C-14) - sc-65096 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
LASS1 (C-14): sc-65096. Western blot analysis of LASS1 expression in non-transfected 293T: sc-117752 (A), human LASS1 transfected 293T: sc-111580 (B) and Daoy (C) whole cell lysates.

LASS1 (D-15) - sc-65097 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
LASS1 (D-15): sc-65097. Immunoperoxidase staining of formalin fixed, paraffin-embedded human epididymis tissue showing cytoplasmic and membrane staining of glandular cells.

LASS1 (H-170) - sc-135033 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
LASS1 (H-170): sc-135033. Western blot analysis of LASS1 expression in U-251-MG (A), HeLa (B), LNCaP (C), mouse brain (D), MCF7 (E) and DU 145 (F) whole cell lysates.

LASS1 (I-16) - sc-65098 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-Ceramide synthase 1 antibody - ab198799 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of paraffin-embedded Human ovarian cancer tissue labeling Ceramide synthase 1 with ab198799 at 1/20 dilution.

Anti-Ceramide synthase 1 antibody - ab56992 from Abcam

Host Mouse
Clonality Monoclonal
Western blot against tagged recombinant protein immunogen using ab56992 LASS1 antibody at 1ug/ml.

Anti-Ceramide synthase 1 antibody - ab98062 from Abcam

Prices $370.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-Ceramide synthase 1 antibody (ab98062) at 1 µg/ml (in 5% skim milk / PBS buffer) + OVCAR-3 Cell Lysate at 10 µgSecondaryHRP conjugated anti-Rabbit IgG at 1/50000 dilution

Anti-Ceramide synthase 1 antibody - ab79578 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-Ceramide synthase 1 antibody [EPR5816(2)] - ab131169 from Abcam

Prices $313.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR5816(2)
Anti-Ceramide synthase 1 antibody [EPR5816(2)] (ab131169) at 1/1000 dilution + Human fetal brain lysate at 10 µgSecondaryGoat Anti-rabbit HRP at 1/2000 dilution

Anti-LASS1 Antibody (C-Terminus) - LS-C140567 from LifeSpan Bioscience

Prices $360.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-LASS1 Antibody - LS-C140568 from LifeSpan Bioscience

Prices $360.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-LASS1 Antibody (aa301-350) - LS-C308718 from LifeSpan Bioscience

Prices $455.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-LASS1 Antibody (Internal, clone EPR5816(2)) - LS-C154535 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR5816(2)
Western blot analysis on fetal brain lysate using anti-LASS1 antibody.

Anti-LASS1 Antibody (aa318-329) - LS-C112713 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
LASS1 antibody (1 ug/ml) staining of Frontal Cortex lysate (35 ug protein/ml in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Anti-LASS1 Antibody (C-Terminus) - LS-C107652 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
LASS1 antibody LS-C107652 Western blot of OVCAR-3 cell lysate.

Anti-LASS1 Antibody - LS-C140584 from LifeSpan Bioscience

Prices $460.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of LAG1 longevity assurance homolog 1 (LS-C140584) at 5 ug/ml on human brain lysate 14 ug/lane. Lane A] antibody alone, Lane B] antibody with 45 ug blocking peptide, Lane C] conjugate alone. Visualized using Pierce West Femto substrate system. Anti Rabbit secondary used at 1:3.5K dilution. Exposure for 5 min

Anti-LASS1 Antibody - LS-C140585 from LifeSpan Bioscience

Prices $460.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of Lass 1 (LS-C140585) at 5 ug/ml on Human Brain lysate 14 ug/lane. Lane A] antibody alone, Lane B] antibody with 45 ug peptide, Lane C] antibody with nonspecific peptide, D]conjugate alone. Visualized using Pierce West Femto substrate system. Anti Rabbit secondary used at 1:3.5K dilution. Exposure for 5 minutes

LASS1 Antibody - NBP1-59733 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: LASS1 Antibody [NBP1-59733] - Human neuroblastoma cells untreated or treated with various drugs. Image from verified customer review.

LASS1 Antibody - NBP1-92067 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunocytochemistry/Immunofluorescence: LASS1 Antibody [NBP1-92067] - Staining of human cell line U-251 MG shows positivity in cytoplasm and centrosome.

LASS1 Antibody - H00010715-A01 from Novus Biologicals

Prices $269.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal

LASS1 Antibody - NBP1-28480 from Novus Biologicals

Prices $299.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

LASS1 Antibody (2E8) - H00010715-M01 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 2E8

Monoclonal Anti-LASS1 antibody produced in mouse - WH0010715M1 from Sigma-Aldrich

Prices $347.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 2E8
<B>Immunoblotting</B><BR/>Monoclonal Anti-LASS1, <B>Cat. No. WH0010715M1</B> used at the antibody concentration: 1 μg/mL. Specific band of ~31.61 kDa using immunogen protein lysate.

Anti-CERS1 antibody produced in rabbit - HPA045724 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-CERS1: <B>Cat. No. HPA045724</B>: Immunohistochemical staining of human hippocampus shows strong cytoplasmic positivity in neuronal cells.

Anti-LASS1 antibody produced in goat - SAB2501185 from Sigma-Aldrich

Prices $376.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-LASS1: <B>Cat. No. SAB2501185</B>: (1 μg/mL) staining of Frontal Cortex lysate (35 μg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
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