PPP1R12A

Gene Symbol PPP1R12A
Entrez Gene 4659
Alt Symbol M130, MBS, MYPT1
Species Human
Gene Type protein-coding
Description protein phosphatase 1, regulatory subunit 12A
Other Description myosin binding subunit|myosin phosphatase, target subunit 1|myosin phosphatase-targeting subunit 1|protein phosphatase 1 regulatory subunit 12A|protein phosphatase 1, regulatory (inhibitor) subunit 12A|protein phosphatase myosin-binding subunit
Swissprots Q86WU3 Q9BYH0 B4DZ09 Q2NKL4 O14974 Q8NFR6 F8VWB4 Q569H0
Accessions BAB39107 EAW97351 EAW97352 EAW97353 EAW97354 EAW97355 EAW97356 O14974 AF086032 AF458589 AAM49717 AK057712 AK125671 AK302692 BAG63921 AK314193 BAG36872 AY380574 AAQ88438 BC000812 BC013941 AAH13941 BC040375 BC047898 AAH47898 BC062560 BC092481 AAH92481 BC111752 AAI11753 D87930 BAA22378 DC350703 XM_005268887 XP_005268944 XM_011538374 XP_011536676 XM_011538375 XP_011536677 XM_011538376 XP_011536678 XM_011538377 XP_011536679 XM_011538378 XP_011536680 XM_011538379 XP_011536681 XM_011538380 XP_011536682 XM_011538381 XP_011536683 XM_011538382 XP_011536684 XM_011538383 XP_011536685 XM_011538384 XP_011536686 XM_011538385 XP_011536687 XR_944554 NM_001143885 NP_001137357 NM_001143886 NP_001137358 NM_001244990 NP_001231919 NM_001244992 NP_001231921 NM_002480 NP_002471
Function Key regulator of protein phosphatase 1C (PPP1C). Mediates binding to myosin. As part of the PPP1C complex, involved in dephosphorylation of PLK1. Capable of inhibiting HIF1AN- dependent suppression of HIF1A activity. {ECO:0000269|PubMed:18477460, ECO:0000269|PubMed:19245366, ECO:0000269|PubMed:20354225}.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:12923170, ECO:0000269|PubMed:18477460}. Note=Along actomyosin filaments and stress fibers.
Tissue Specificity Expressed in striated muscles, specifically in type 2a fibers (at protein level). {ECO:0000269|PubMed:20634291}.
Top Pathways Focal adhesion, Vascular smooth muscle contraction, Oxytocin signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway

Mouse/Human/Rat Phospho-PPP1R12A / MYPT1 (Thr853) ELISA Kit (Cell-Based Phosphorylation ELISA) - LS-F1191 from LifeSpan Bioscience

Category ELISA Kit
Prices $550.00
Sizes 1 plate

Mouse/Human/Rat PPP1R12A / MYPT1 ELISA Kit (Cell-Based ELISA) - LS-F2177 from LifeSpan Bioscience

Category ELISA Kit
Prices $450.00
Sizes 1 plate

Soluble CD163 (sCD163), Human, ELISA Kit - CSB-E14050h from ARP American Research Products

Category ELISA Kit
Prices $495.00, $685.00, $686.00, $689.00
Sizes 48 t, 96 t, 5 x 96t, 10 x 96t
Sensitivity 0.039 ng/ml
Range 0.156 ng/ml-10 ng/ml

MYPT1 Colorimetric Cell-Based ELISA Kit - CB5479 from Assay Biotechnology

Category ELISA Kit
Prices $380.00, $760.00, $1,140.00
Sizes 1 kit, 2 kits, 3 kits
Range > 5000 Cells

MYPT1 (Phospho-Thr853) Colorimetric Cell-Based ELISA Kit - CBP1182 from Assay Biotechnology

Category ELISA Kit
Prices $480.00, $960.00, $1,440.00
Sizes 1 kit, 2 kits, 3 kits
Range > 5000 Cells

protein phosphatase 1, regulatory (inhibitor) subunit 12A, ELISA Kit - MBS9332129 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

ELISA Kit for Cluster Of Differentiation (CD163) - SEB726Hu from Cloud-clone

Category ELISA Kit
Sensitivity The minimum detectable dose of this kit is typically less than 0.282ng/mL.
Range 0.625-40ng/mL The standard curve concentrations used for the ELISA's were 40ng/mL, 20ng/mL, 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL

Human sCD163(Soluable Cluster of Differentiation 163) ELISA Kit - E-EL-H0036 from Iwai North America Inc.

Category ELISA Kit
Prices $580.00
Sizes 1 kit
Sensitivity 0.94 ng/mL
Range 1.56~100 ng/mL

Human CA9 (Carbonic Anhydrase IX) CLIA Kit - E-CL-H0015 from Iwai North America Inc.

Category CLIA Kit
Prices $722.50
Sizes 1 kit
Sensitivity 9.375pg/mL
Range 15.625-1000pg/mL

MYPT1 ELISA Kit - DEIA-XYA1297 from Creative Diagnostics

Category ELISA Kit

MYPT1 (Phospho-Thr853) ELISA Kit - DEIA-XYA1298 from Creative Diagnostics

Category ELISA Kit

Human MBS ELISA Kit - abx573587 from Abbexa

Category ELISA Kit
Sensitivity 0.27 ng/ml
Range 0.781 ng/ml - 50 ng/ml

Human PPP1R12A ELISA Kit - E031709 from Biobool

Category ELISA Kit

Human Soluble CD163 (sCD163) ELISA Kit - AE61505HU from ARP American Research Products

Category ELISA Kit
Prices $549.00
Sizes 96 t
Sensitivity 0.273 ng/mL
Range 0.625-40 ng/mL

MYPT1 Colorimetric Cell-Based ELISA Kit - EKA50412 from Biomatik

Category ELISA Kit
Prices $399.00
Sizes 96 tests
Sensitivity At least 5000 cells/well
Range Qualitative
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