LTF

Gene Symbol LTF
Entrez Gene 4057
Alt Symbol GIG12, HEL110, HLF2, LF
Species Human
Gene Type protein-coding
Description lactotransferrin
Other Description epididymis luminal protein 110|growth-inhibiting protein 12|kaliocin-1|lactoferricin|lactoferroxin|neutrophil lactoferrin|talalactoferrin
Swissprots O00756 Q96KZ4 Q8IU92 Q16789 Q9UCY5 Q96KZ5 P02788 Q8TCD2 E7EQH5 Q5DSM0 Q9H1Z3 Q8IZH6 Q16785 Q16786 A8K9U8 B2MV13 Q16780 B7Z4X2
Accessions AAA59479 AAB24877 AAB57795 AAN84790 AAO14686 ACC95966 ACC95967 EAW64767 P02788 AF332168 AAG48753 AK093852 BAG52774 AK290859 BAF83548 AK292813 BAF85502 AK298035 BAH12708 AK303889 BAG64824 AK303995 BAG64912 AK316330 BAH14701 AY137470 AAN11304 AY165046 AAN63998 AY178998 AAN75578 AY360320 AAR12276 AY493417 AAS72878 AY875691 AAW71443 BC015822 AAH15822 BC015823 AAH15823 BC022347 AAH22347 BP342557 CD722125 DQ522304 ABF69105 DQ892855 ABM83781 DQ896102 ABM87101 EU779935 ACF19793 EU794669 ACJ13723 KF992208 AHL67504 M18642 AAA86665 M83202 AAA59511 M83205 AAA58656 M93150 AAA36159 U07643 AAB60324 U84119 X52941 CAA37116 X53961 CAA37914 NM_001199149 NP_001186078 NM_002343 NP_002334
Function Isoform DeltaLf: transcription factor with antiproliferative properties and ability to induce cell cycle arrest. Binds to the DeltaLf response element found in the SKP1, BAX, DCPS, and SELH promoters.
Subcellular Location Isoform 1: Secreted. Cytoplasmic granule. Note=Secreted into most exocrine fluids by various endothelial cells. Stored in the secondary granules of neutrophils.
Tissue Specificity High levels are found in saliva and tears, intermediate levels in serum and plasma, and low levels in urine. In kidney, detected in the distal collecting tubules in the medulla but not in the cortical region or in blood vessels. Detected in peripheral blood neutrophils (at protein level). Isoform 1 and isoform DeltaLf are expressed in breast, prostate, spleen, pancreas, kidney, small intestine, lung, skeletal muscle, uterus, thymus and fetal liver. Isoform 1 is expressed in brain, testis and peripheral blood leukocytes; isoform DeltaLf is barely detectable in these tissues. Isoform DeltaLf is expressed in placenta, liver and ovary; isoform 1 is barely detectable in these tissues. In kidney, isoform 1 is expressed at high levels in the collecting tubules of the medulla but at very low levels in the cortex. {ECO:0000269|PubMed:10792619, ECO:0000269|PubMed:2981589, ECO:0000269|PubMed:9122171}.

lactoferrin (N-20) - sc-14431 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
lactoferrin (N-20): sc-14431. Western blot analysis of lactoferrin expression in human PBL whole cell lysate.

lactoferrin (H-65) - sc-25622 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
lactoferrin (H-65): sc-25622. Western blot analysis of lactoferrin expression in human PBL whole cell lysate.

lactoferrin (C-15) - sc-14434 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
lactoferrin (C-15): sc-14434. Western blot analysis of lactoferrin expression in non-transfected: sc-117752 (A) and mouse lactoferrin transfected: sc-121272 (B) 293T whole cell lysates.

lactoferrin (B97) - sc-53498 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
lactoferrin (B97): sc-53498. Indirect, intracellular FCM analysis of fixed and permeabilized human peripheral blood leukocytes stained with lactoferrin (B97), followed by FITC-conjugated goat anti-mouse IgG: sc-2010. Black line histogram represents the isotype control, normal mouse IgG: sc-2025.

lactoferrin (KT33) - sc-101487 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal
lactoferrin (KT33): sc-101487. Western blot analysis of lactoferrin expression in non-transfected 293T: sc-117752 (A), mouse lactoferrin transfected 293T: sc-121272 (B) and human PBL (C) whole cell lysates.

lactoferrin (LF-10) - sc-80549 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal

lactoferrin (a-bC-lobe) - sc-52694 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal
lactoferrin (a-bC-lobe): sc-52694. Western blot analysis of lactoferrin expression in human PBL whole cell lysate.

lactoferrin (1A1) - sc-52048 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal
lactoferrin (1A1): sc-52048. Western blot analysis of lactoferrin expression in human PBL whole cell lysate.

Anti-Lactoferrin antibody - ab15811 from Abcam

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-Lactoferrin antibody (ab15811) at 1/500 dilution + Human Lactoferrin

Anti-Lactoferrin antibody - ab77548 from Abcam

Prices $384.00
Sizes 200 µl
Host Goat
Clonality Polyclonal
Anti-Lactoferrin antibody (ab77548) at 0.05 µg/ml + Human Peripheral Blood Mononucleocyte lysate (in RIPA buffer) at 35 µgObserved band size : 85 kDa (why is the actual band size different from the predicted?)

Anti-Lactoferrin antibody - ab197811 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-Lactoferrin antibody (ab197811) at 1/400 dilution + Human prostate lysate at 40 µg

Anti-Lactoferrin antibody - ab135710 from Abcam

Prices $376.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-Lactoferrin antibody (ab135710) at 1/100 dilution + MDA-MB231 cell line lysate at 35 µg

Anti-Lactoferrin antibody - ab77780 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Lactoferrin antibody (ab77780)Lane 1 : Human Plasma Total ProteinLane 2 : Human Prostate Tissue LysateLane 3 : Human Lung Tissue Lysate Lysates/proteins at 10 µg per lane.SecondaryGoat polyclonal to Rabbit IgG - H&L - Pre-Adsorbed (HRP) at 1/3000 dilutiondeveloped using the ECL techniquePerformed under reducing conditions.

Anti-Lactoferrin antibody - ab115298 from Abcam

Prices $376.00
Sizes 50 µg
Host Goat
Clonality Polyclonal
ab115298 at 2 &microg/ml, staining Lactoferrin in formalin-fixed, paraffin-embedded Human Neutrophils followed by biotinylated anti-goat IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.

Anti-Lactoferrin antibody - ab124426 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Lactoferrin antibody (ab124426) at 1/2000 dilutionLane 1 : Lactoferrin protein at 0.02 µgLane 2 : Lactoferrin protein at 0.05 µg

Anti-Lactoferrin antibody [1A1] (HRP) - ab24476 from Abcam

Prices $370.00
Sizes 200 µg
Host Mouse
Clonality Monoclonal
Clone 1A1

Anti-Lactoferrin antibody [1C6] - ab38155 from Abcam

Prices $379.00
Sizes 250 µg
Host Mouse
Clonality Monoclonal
Clone 1C6

Anti-Lactoferrin antibody [1C6] (HRP) - ab10109 from Abcam

Prices $370.00
Sizes 200 µg
Host Mouse
Clonality Monoclonal
Clone 1C6

Anti-Lactoferrin antibody [2B8] - ab10110 from Abcam

Prices $398.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 2B8
Standard curve for Lactoferrin (Analyte: ab78526); dilution range 1pg/ml to 1µg/ml using Capture Antibody Mouse monoclonal [2B8] to Lactoferrin (ab10110) at 1µg/ml and Detector Antibody Rabbit polyclonal to Lactoferrin (Biotin) (ab25811) at 0.5µg/ml.

Anti-Lactoferrin antibody [67D9] - ab166803 from Abcam

Prices $376.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 67D9
Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human spleen neutrophils labeling Lactoferrin with ab166803 at 1/100 dilution.

Anti-Lactoferrin antibody [B97] - ab6410 from Abcam

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone B97

Anti-Lactoferrin antibody (Biotin) - ab25811 from Abcam

Prices $379.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Standard curve for Lactoferrin (Analyte: ab78526); dilution range 1pg/ml to 1µg/ml using Capture Antibody Mouse monoclonal [2B8] to Lactoferrin (ab10110) at 1µg/ml and Detector Antibody Rabbit polyclonal to Lactoferrin (Biotin) (ab25811) at 0.5µg/ml.

Anti-Lactoferrin antibody [EPR4337] - ab109216 from Abcam

Prices $379.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR4337
All lanes : Anti-Lactoferrin antibody [EPR4337] (ab109216) at 1/1000 dilutionLane 1 : PBMC lysateLane 2 : Hela lysateLane 3 : Fetal kidney lysateLane 4 : Human milk lysateLysates/proteins at 10 µg per lane.SecondaryHRP labelled goat anti-rabbit at 1/2000 dilution

Anti-Lactoferrin antibody [EPR4338] - ab109000 from Abcam

Prices $385.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR4338
Anti-Lactoferrin antibody [EPR4338] (ab109000) at 1/1000 dilution + Human peripheral blood mononuclear cell (PBMC) lysate at 10 µg

Anti-Lactoferrin antibody (FITC) - ab136186 from Abcam

Prices $378.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-Lactoferrin antibody (FITC) (ab136186) at 1/500 dilution + Lactoferrin protein
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