Gene Symbol | NFKBIE |
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Entrez Gene | 4794 |
Alt Symbol | IKBE |
Species | Human |
Gene Type | protein-coding |
Description | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon |
Other Description | I-kappa-B-epsilon|NF-kappa-B inhibitor epsilon|NF-kappa-BIE|ikB-E|ikB-epsilon|ikappaBepsilon |
Swissprots | Q5T9V9 O00221 |
Accessions | AAM27002 AAV31776 EAX04262 EAX04263 EAX04264 O00221 AK130739 BAC85418 AK301360 BAH13464 BC011676 AAH11676 BC063609 AAH63609 BC166665 AAI66665 BG759212 BX367256 U91616 AAC51216 NM_004556 NP_004547 |
Function | Inhibits NF-kappa-B by complexing with and trapping it in the cytoplasm. Inhibits DNA-binding of NF-kappa-B p50-p65 and p50-c-Rel complexes. {ECO:0000269|PubMed:9315679}. |
Subcellular Location | Cytoplasm {ECO:0000250}. |
Tissue Specificity | Highly expressed in spleen, testis and lung, followed by kidney, pancreas, heart, placenta and brain. Also expressed in granulocytes and macrophages. |
Top Pathways | T cell receptor signaling pathway, B cell receptor signaling pathway, Adipocytokine signaling pathway, Neurotrophin signaling pathway, Epstein-Barr virus infection |
NFKBIE / IKB Epsilon Antibody Blocking Peptide - LS-E13837 from LifeSpan Bioscience
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IkB-epsilon Partial Recombinant Protein - H00004794-Q01 from Novus Biologicals
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NFKBIE Blocking Peptide - 33R-1862 from Fitzgerald
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Human IkBe Protein - abx067216 from Abbexa
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NFKBIE / IKBE - H00004794-Q01-10 from Acris Antibodies
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NFKBIE / IKBE - H00004794-Q01-25 from Acris Antibodies
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Inhibitory Subunit Of NF Kappa B Epsilon (IkBe), Human - 20-8970 from ARP American Research Products
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NFKBIE fusion protein - Ag1800 from Proteintech Group
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Recombinant Human NFKBIE, His-tagged - NFKBIE-28876TH from Creative Biomart
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Recombinant Human NFKBIE, GST-tagged - NFKBIE-1283H from Creative Biomart
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Recombinant Inhibitory Subunit Of NF Kappa B Epsilon (IkBe) - RPE700Hu01 from Uscn Life Science Inc.
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Recombinant Inhibitory Subunit Of NF Kappa B Epsilon (IkBe) - RPE700Mu01 from Uscn Life Science Inc.
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IKB-ε (D17) Peptide - BS1191P from Bioworld Technology
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p-IkB-ε (S22) Peptide - BS4107P from Bioworld Technology
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Recombinant Inhibitory Subunit Of NF Kappa B Epsilon (IkBe) - RPE700Hu01 from Cloud-clone
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Recombinant Human NF-kappa-B inhibitor epsilon(NFKBIE) - CSB-YP015764HU CSB-EP015764HU CSB-BP015764HU CSB-MP015764HU from Cusabio
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IKB epsilon Blocking Peptide - abx161691 from Abbexa
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NFKBIE Protein - abx163603 from Abbexa
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NFKBIE / IKBE (N-term HIS tag) - TP760703 from Acris Antibodies
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IkB-epsilon Recombinant Protein Antigen - NBP1-87763PEP from Novus Biologicals
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IkB-epsilon Protein - NBP1-87762PEP from Novus Biologicals
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NFKBIE-Blocking-Peptide-Center - BP21219c from Abgent, a WuXi AppTec company
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NFKBIE-Blocking-Peptide-N-term - BP21348a from Abgent, a WuXi AppTec company
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NFKBIE Peptide, Human - M34GP10346H from Creative Peptides
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IKB epsilon Blocking Peptide - CBP4480 from Cohesion Biosciences
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