JUP

Gene Symbol	JUP
Entrez Gene	3728
Alt Symbol	ARVD12, CTNNG, DP3, DPIII, PDGB, PKGB
Species	Human
Gene Type	protein-coding
Description	junction plakoglobin
Other Description	catenin (cadherin-associated protein), gamma 80kDa|desmoplakin III|desmoplakin-3
Swissprots	Q9BWC4 Q9HCX9 Q7L3S5 Q15151 P14923 Q86W21 Q15093
Accessions	AAG16727 BAA09435 CAC04246 CAP07504 CAP11472 CAR97086 CAT82323 CCQ43676 EAW60762 EAW60763 EAW60764 EAW60765 P14923 AK226051 AY243535 AAO85780 BC000441 AAH00441 BC011865 AAH11865 DQ891420 ABM82346 DQ894594 ABM85520 M23410 AAA64895 Z68228 CAA92522 XM_006721873 XP_006721936 XM_006721874 XP_006721937 XM_006721875 XP_006721938 XM_006721878 XP_006721941 XM_011524753 XP_011523055 XM_011524754 XP_011523056 XM_011524755 XP_011523057 XM_011524756 XP_011523058 XM_011524757 XP_011523059 XM_011524758 XP_011523060 NM_002230 NP_002221 NM_021991 NP_068831
Function	Common junctional plaque protein. The membrane- associated plaques are architectural elements in an important strategic position to influence the arrangement and function of both the cytoskeleton and the cells within the tissue. The presence of plakoglobin in both the desmosomes and in the intermediate junctions suggests that it plays a central role in the structure and function of submembranous plaques. Acts as a substrate for VE-PTP and is required by it to stimulate VE- cadherin function in endothelial cells. Can replace beta-catenin in E-cadherin/catenin adhesion complexes which are proposed to couple cadherins to the actin cytoskeleton (By similarity). {ECO:0000250}.
Subcellular Location	Cell junction, adherens junction {ECO:0000269|PubMed:22781308}. Cell junction, desmosome {ECO:0000269|PubMed:22781308}. Cytoplasm, cytoskeleton {ECO:0000269|PubMed:22781308}. Membrane {ECO:0000269|PubMed:22781308}; Peripheral membrane protein {ECO:0000269|PubMed:22781308}. Note=Cytoplasmic in a soluble and membrane-associated form.
Top Pathways	Acute myeloid leukemia, Arrhythmogenic right ventricular cardiomyopathy (ARVC), Transcriptional misregulation in cancer

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Mouse/Human/Rat JUP/CTNNG/Junction Plakoglobin ELISA Kit (Cell-Based ELISA) - LS-F1860 from LifeSpan Bioscience Category ELISA Kit Prices $450.00 Sizes 1 plate Range 0.156-10 ng/ml

Human JUP/CTNNG/Junction Plakoglobin ELISA Kit (Sandwich ELISA) - LS-F7467 from LifeSpan Bioscience Category ELISA Kit Prices $720.00 Sizes 1 plate Sensitivity 0.062 ng/ml Range 0.156-10 ng/ml

Human Junction Plakoglobin ELISA Kit - abx152078 from Abbexa Category ELISA Kit Sensitivity 0.054 ng/ml Range 0.156 ng/ml - 10 ng/ml

Junction plakoglobin (JUP), Human, ELISA Kit - E01J0005 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t

Junction Plakoglobin, ELISA Kit - MBS056581 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Junction Plakoglobin, ELISA Kit - MBS060422 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Junction Plakoglobin, ELISA Kit - MBS093746 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Junction Plakoglobin, ELISA Kit - MBS065904 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Junction Plakoglobin, ELISA Kit - MBS058994 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Junction Plakoglobin, ELISA Kit - MBS070047 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 5.0pg/ml. Range 31.2pg/ml-1000pg/ml.

Junction Plakoglobin, ELISA Kit - MBS098989 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Junction plakoglobin (JUP), ELISA Kit - MBS7206151 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Junction plakoglobin (JUP), ELISA Kit - MBS7204881 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Junction plakoglobin (JUP), ELISA Kit - MBS7200798 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Junction plakoglobin (JUP), ELISA Kit - MBS7225942 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Junction plakoglobin (JUP), ELISA Kit - MBS7219571 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Junction plakoglobin (JUP), ELISA Kit - MBS7201149 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Junction Plakoglobin (JUP), ELISA Kit - MBS2018947 from MyBioSource Category ELISA Kit Prices $380.00, $565.00, $765.00, $3,130.00, $5,670.00 Sizes 24 -strip-wells, 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.062ng/mL. Range 0.156-10ng/mL. The standard curve concentrations used for the ELISA's were 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.312ng/mL, 0.156ng/mL.

Junction plakoglobin (JUP), ELISA Kit - MBS7205011 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Junction plakoglobin (JUP), ELISA Kit - MBS7242928 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Junction plakoglobin (JUP), ELISA Kit - MBS7222980 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Junction plakoglobin (JUP), ELISA Kit - MBS7241963 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Junction plakoglobin (JUP), ELISA Kit - MBS7209455 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Junction plakoglobin (JUP), ELISA Kit - MBS7223033 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Catenin-gamma Colorimetric Cell-Based ELISA Kit - CB5107 from Assay Biotechnology Category ELISA Kit Prices $380.00, $760.00, $1,140.00 Sizes 1 kit, 2 kits, 3 kits Range > 5000 Cells

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