CNTN1

Gene Symbol	CNTN1
Entrez Gene	1272
Alt Symbol	F3, GP135, MYPCN
Species	Human
Gene Type	protein-coding
Description	contactin 1
Other Description	contactin-1|glycoprotein gP135|neural cell surface protein F3
Swissprots	Q7M4P0 A8K0Y3 Q8N466 Q14030 Q12860 Q12861 A8K0H9
Accessions	EAW57822 EAW57823 EAW57824 Q12860 AI473107 AK289544 BAF82233 AK289698 BAF82387 BC036569 AAH36569 BM717031 BX648591 BY799936 DA215712 DQ442053 DQ442054 U07819 AAA67920 U07820 AAA67921 Z21488 CAA79696 XM_005268651 XP_005268708 XM_006719241 XP_006719304 XM_011537926 XP_011536228 XM_011537927 XP_011536229 NM_001256063 NP_001242992 NM_001256064 NP_001242993 NM_001843 NP_001834 NM_175038 NP_778203
Function	Contactins mediate cell surface interactions during nervous system development. Involved in the formation of paranodal axo-glial junctions in myelinated peripheral nerves and in the signaling between axons and myelinating glial cells via its association with CNTNAP1. Participates in oligodendrocytes generation by acting as a ligand of NOTCH1. Its association with NOTCH1 promotes NOTCH1 activation through the released notch intracellular domain (NICD) and subsequent translocation to the nucleus. Interaction with TNR induces a repulsion of neurons and an inhibition of neurite outgrowth (By similarity). {ECO:0000250}.
Subcellular Location	Isoform 1: Cell membrane; Lipid-anchor, GPI- anchor; Extracellular side.
Tissue Specificity	Strongly expressed in brain and in neuroblastoma and retinoblastoma cell lines. Lower levels of expression in lung, pancreas, kidney and skeletal muscle. {ECO:0000269|PubMed:2026173, ECO:0000269|PubMed:8164510}.
Top Pathways	Cell adhesion molecules (CAMs)

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human Contactin 1 full length protein - ab109353 from Abcam Category Protein Source HEK 293 cells Species Human

Human Contactin 1 peptide - ab74597 from Abcam Category Peptide

Human Contactin 1 peptide - ab74598 from Abcam Category Peptide

CNTN1 / gp135 / Contactin 1 Antibody Blocking Peptide - LS-E21739 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

CNTN1 / gp135 / Contactin 1 Antibody Blocking Peptide - LS-E10160 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Coagulation Factor III/Tissue Factor Recombinant Protein - P3830 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Coagulation Factor III/Tissue Factor Partial Recombinant Protein - H00002152-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human Coagulation Factor III/Tissue Factor Protein - NBP2-22785 from Novus Biologicals Category Protein Prices $269.00 Sizes 20 µg Species Human

Coagulation Factor III/Tissue Factor Recombinant Protein - H00002152-G01 from Novus Biologicals Category Protein Prices $579.00 Sizes 10 µg Species Human

CNTN1-Antibody-Center-Blocking-Peptide - BP9490c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Recombinant Human Contactin-1 Fc Chimera, CF - 904-CN-100 from R&D Systems Category Protein Source Spodoptera frugiperda, Sf 21 (baculovirus)-derived

Human CNTN1 His tag protein - orb82913 from Biorbyt Category Protein Prices $400.00, $612.00 Sizes 100 μg, 200 μg Source Human Species Human

Human Contactin 1 Protein - abx066110 from Abbexa Category Protein Source E.coli Species Human

Contactin 1 (CNTN1), Human - 20-7536 from ARP American Research Products Category Protein Prices $399.00 Sizes 50 µg Source E.coli Species Human

CNTN1 fusion protein - Ag4803 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

CNTN1 fusion protein - Ag5030 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

F3 Human Protein - GWB-BSP693 from Genway Biotech Category Protein Prices $75.00, $165.00, $5,700.00 Sizes 2 μg, 10 μg, 1000 μg Source Escherichia Coli. Species Human

Recombinant Human Contactin 1 - CNTN1-1597H from Creative Biomart Category Protein Source Sf 21 Insect Cells.

Recombinant Human CNTN1, Fc-His tagged - CNTN1-669H from Creative Biomart Category Protein Source Human Cells Species Human

Recombinant Human CNTN1, His tagged - CNTN1-670H from Creative Biomart Category Protein Source Human Cells Species Human

Recombinant Human CNTN1, Fc-tagged - CNTN1-26257TH from Creative Biomart Category Protein Source HEK 293 cells

Recombinant Human CNTN1, GST-tagged - CNTN1-11411H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human CNTN1, Fc-tagged - CNTN1-166H from Creative Biomart Category Protein Source HEK293 Cells Species Human

Recombinant Human CNTN1, Fc Chimera - CNTN1-507H from Creative Biomart Category Protein Source Baculovirus Sf 21 Insect cells Species Human

CNTN1 - PN201454 from Elabscience Category Protein Prices $225.00, $475.00 Sizes 10 μg, 50 μg Source Human Cells Species Human

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