CNTN1

Gene Symbol	CNTN1
Entrez Gene	1272
Alt Symbol	F3, GP135, MYPCN
Species	Human
Gene Type	protein-coding
Description	contactin 1
Other Description	contactin-1|glycoprotein gP135|neural cell surface protein F3
Swissprots	Q7M4P0 A8K0Y3 Q8N466 Q14030 Q12860 Q12861 A8K0H9
Accessions	EAW57822 EAW57823 EAW57824 Q12860 AI473107 AK289544 BAF82233 AK289698 BAF82387 BC036569 AAH36569 BM717031 BX648591 BY799936 DA215712 DQ442053 DQ442054 U07819 AAA67920 U07820 AAA67921 Z21488 CAA79696 XM_005268651 XP_005268708 XM_006719241 XP_006719304 XM_011537926 XP_011536228 XM_011537927 XP_011536229 NM_001256063 NP_001242992 NM_001256064 NP_001242993 NM_001843 NP_001834 NM_175038 NP_778203
Function	Contactins mediate cell surface interactions during nervous system development. Involved in the formation of paranodal axo-glial junctions in myelinated peripheral nerves and in the signaling between axons and myelinating glial cells via its association with CNTNAP1. Participates in oligodendrocytes generation by acting as a ligand of NOTCH1. Its association with NOTCH1 promotes NOTCH1 activation through the released notch intracellular domain (NICD) and subsequent translocation to the nucleus. Interaction with TNR induces a repulsion of neurons and an inhibition of neurite outgrowth (By similarity). {ECO:0000250}.
Subcellular Location	Isoform 1: Cell membrane; Lipid-anchor, GPI- anchor; Extracellular side.
Tissue Specificity	Strongly expressed in brain and in neuroblastoma and retinoblastoma cell lines. Lower levels of expression in lung, pancreas, kidney and skeletal muscle. {ECO:0000269|PubMed:2026173, ECO:0000269|PubMed:8164510}.
Top Pathways	Cell adhesion molecules (CAMs)

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human CNTN1 / gp135 / Contactin 1 ELISA Kit (Sandwich ELISA) - LS-F4322 from LifeSpan Bioscience Category ELISA Kit Prices $690.00 Sizes 1 plate Sensitivity 0.058 ng/ml Range 0.156-10 ng/ml

Mouse CNTN1 / gp135 / Contactin 1 ELISA Kit (Sandwich ELISA) - LS-F6782 from LifeSpan Bioscience Category ELISA Kit Prices $700.00 Sizes 1 plate Sensitivity 0.053 ng/ml Range 0.156-10 ng/ml

Human CNTN1 / gp135 / Contactin 1 ELISA Kit (Sandwich ELISA) - LS-F11149 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity 0.156 Range 0.156-10 ng/ml

Rat CNTN1 / gp135 / Contactin 1 ELISA Kit (Sandwich ELISA) - LS-F11150 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity 0.156 Range 0.156-10 ng/ml

Human Contactin 1 ELISA Kit - abx051790 from Abbexa Category ELISA Kit Sensitivity 12.5 pg/ml Range 30 pg/ml-1800 pg/ml

Human Contactin 1 ELISA Kit - abx151150 from Abbexa Category ELISA Kit Sensitivity 0.061 ng/ml Range 0.156 ng/ml - 10 ng/ml

Contactin 1, CNTN1, Human, ELISA Kit - E-EL-H1498 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t Sensitivity 0.094 Range 0.156-10ng/mL

Contactin 1 (CNTN1), Human, ELISA Kit - SEB201Hu from ARP American Research Products Category ELISA Kit Prices $685.00 Sizes 96 t Sensitivity 0.061ng/mL Range 0.156-10ng/mL

Contactin 1, Human, ELISA Kit - E01C0408 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t Sensitivity 0.1ng/ml Range 0.5-10 ng/mL,

Contactin-1, CNTN1, Human, ELISA Kit - E15020h from ARP American Research Products Category ELISA Kit Prices $736.00 Sizes 96 t Range 0.156-10 ng/mL

Tissue factor, F3, Human, ELISA Kit - E0524h from ARP American Research Products Category ELISA Kit Prices $476.00 Sizes 96 t Range 15.6-1000 pg/mL

Contactin 1, CNTN1, Mouse, ELISA Kit - E-EL-M0346 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t Sensitivity 0.094 Range 0.156-10ng/mL

Contactin 1, CNTN1, Rat, ELISA Kit - E-EL-R0265 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t Sensitivity 0.094 Range 0.156-10ng/mL

Contactin 1, CNTN1, Rabbit, ELISA Kit - E-EL-RB0411 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Contactin 1, CNTN1, Chicken, ELISA Kit - E-EL-Ch1373 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t

Contactin 1, CNTN1, Porcine, ELISA Kit - E-EL-P1617 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Contactin 1, CNTN1, Guinea Pig, ELISA Kit - E-EL-GP0401 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t

Contactin 1, CNTN1, Monkey, ELISA Kit - E-EL-MK2058 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Contactin 1 (CNTN1), Human, CLIA Kit - SCB201Hu from ARP American Research Products Category CLIA Kit Prices $840.00 Sizes 96 t Sensitivity 0.046ng/mL Range 0.156-10ng/mL

Custom Human Contactin-1 ELISA - ELH-CNTN1 from RayBiotech Category ELISA Kit Prices $615.00, $1,107.00, $2,460.00 Sizes 1 plate kit, 2 plate kit, 5 plate kit

Human CNTN1 ELISA Kit - HC0415 from NeoScientific Category ELISA Kit Prices $495.00 Sizes 96 t

Anserine CNTN1 ELISA Kit - AC0415 from NeoScientific Category ELISA Kit Prices $495.00 Sizes 96 t

Human Contactin 1 (CNTN1) CLIA Kit - DEEL0477 from Creative Diagnostics Category CLIA Kit Sensitivity 0.046 ng/mL Range 0.156-10 ng/mL

Human CNTN1(Contactin 1) ELISA Kit - E-EL-H1498 from Elabscience Category ELISA Kit Sensitivity 0.10 ng/mL Range 0.16—10 ng/mL

Human CNTN1 (Contactin 1) CLIA Kit - E-CL-H0966 from Elabscience Category CLIA Kit Sensitivity 18.75 pg/mL Range Average Recovery (%)

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