MCM4

Gene Symbol MCM4
Entrez Gene 4173
Alt Symbol CDC21, CDC54, NKCD, NKGCD, P1-CDC21, hCdc21
Species Human
Gene Type protein-coding
Description minichromosome maintenance complex component 4
Other Description CDC21 homolog|DNA replication licensing factor MCM4|homolog of S. pombe cell devision cycle 21|minichromosome maintenance deficient 4
Swissprots Q8NEH1 P33991 Q99658
Accessions AAB51723 AAC52018 AAS83108 CBX85473 EAW86684 EAW86685 EAW86686 P33991 AK022899 BAG51132 AK296913 BAG59468 AK309812 AM493756 CAM35476 BC031061 AAH31061 BF793151 BM781972 BQ058022 BQ689703 X74794 CAA52801 XM_005251234 XP_005251291 NM_005914 NP_005905 NM_182746 NP_877423
Function Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity. {ECO:0000269|PubMed:9305914}.
Subcellular Location Nucleus {ECO:0000250}.
Top Pathways DNA replication, Cell cycle

MCM4 CRISPR/Cas9 KO Plasmid (h) - sc-402451 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

MCM4 HDR Plasmid (h) - sc-402451-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MCM4 Double Nickase Plasmid (h) - sc-402451-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MCM4 Double Nickase Plasmid (h2) - sc-402451-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MCM4 CRISPR Activation Plasmid (h) - sc-402451-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

MCM4 CRISPR Activation Plasmid (h2) - sc-402451-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

MCM4 Lentiviral Activation Particles (h) - sc-402451-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MCM4 Lentiviral Activation Particles (h2) - sc-402451-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MCM4 siRNA (h) - sc-37619 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MCM4 shRNA Plasmid (h) - sc-37619-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MCM4 shRNA (h) Lentiviral Particles - sc-37619-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MCM4 RNAi - H00004173-R04 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MCM4 RNAi - H00004173-R03 from Novus Biologicals

Category siRNA
Prices $409.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU081181 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN13121 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND13121 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MCM4 siRNA (Human) - CRH2841 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human MCM4 (NM_005914.3) - SHH339311 from Creative biogene

Category siRNA
Species Reactivities Human

MCM4 shRNA Plasmid (Human) - CHH2841 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

MCM4 miRNA 3'UTR clone - MiUTR3H-05161 from Creative biogene

Species Reactivities Human

MCM4 miRNA 3'UTR clone - MiUTR3H-05162 from Creative biogene

Species Reactivities Human
Search more