MCM4

Gene Symbol	MCM4
Entrez Gene	4173
Alt Symbol	CDC21, CDC54, NKCD, NKGCD, P1-CDC21, hCdc21
Species	Human
Gene Type	protein-coding
Description	minichromosome maintenance complex component 4
Other Description	CDC21 homolog|DNA replication licensing factor MCM4|homolog of S. pombe cell devision cycle 21|minichromosome maintenance deficient 4
Swissprots	Q8NEH1 P33991 Q99658
Accessions	AAB51723 AAC52018 AAS83108 CBX85473 EAW86684 EAW86685 EAW86686 P33991 AK022899 BAG51132 AK296913 BAG59468 AK309812 AM493756 CAM35476 BC031061 AAH31061 BF793151 BM781972 BQ058022 BQ689703 X74794 CAA52801 XM_005251234 XP_005251291 NM_005914 NP_005905 NM_182746 NP_877423
Function	Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity. {ECO:0000269|PubMed:9305914}.
Subcellular Location	Nucleus {ECO:0000250}.
Top Pathways	DNA replication, Cell cycle

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human MCM4 full length protein - ab131916 from Abcam Category Protein Source Wheat germ Species Human

MCM4 Antibody Blocking Peptide - LS-E3359 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

MCM4 Antibody Blocking Peptide - LS-E13141 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

MCM4 Antibody Blocking Peptide - LS-E13140 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

MCM4 Antibody Blocking Peptide - LS-E13149 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

MCM4 Antibody Blocking Peptide - LS-E13150 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human MCM4 Protein - H00004173-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human MCM4 Protein - H00004173-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

MCM4-Antibody-C-term-Blocking-Peptide - BP14534b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

MCM4 Blocking Peptide - 33R-4325 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

MCM4 Blocking Peptide - 33R-9921 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

MCM4 Blocking Peptide - 33R-8784 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

MCM4 (phospho-Ser54) Blocking Peptide - abx062922 from Abbexa Category Peptide Species Human, Mouse, Rat

MCM4 Blocking Peptide - abx062923 from Abbexa Category Peptide Species Human

MCM4 - H00004173-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

MCM4 - H00004173-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

MCM4 - H00004173-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

MCM4 - H00004173-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

MCM4 fusion protein - ag3703 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Human MCM4, His-tagged - MCM4-28040TH from Creative Biomart Category Protein Source E. coli

MCM4 (pS54) Blocking Peptide - CBP1728 from Cohesion Biosciences Category Peptide Prices $150.00, $450.00 Sizes 1 mg, 5 mg Species Human, Mouse, Rat

MCM4 Blocking Peptide - CBP1729 from Cohesion Biosciences Category Peptide Prices $100.00, $300.00 Sizes 1 mg, 5 mg Species Human

MCM4 (P50) Peptide - BS3249P from Bioworld Technology Category Peptide Prices $158.00 Sizes 100 µl

p-MCM4 (S54) Peptide - BS4843P from Bioworld Technology Category Peptide Prices $158.00 Sizes 100 µl

Recombinant Human DNA replication licensing factor MCM4(MCM4) ,partial - CSB-YP013594HU CSB-EP013594HU CSB-BP013594HU CSB-MP013594HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

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