MCM4

Gene Symbol MCM4
Entrez Gene 4173
Alt Symbol CDC21, CDC54, NKCD, NKGCD, P1-CDC21, hCdc21
Species Human
Gene Type protein-coding
Description minichromosome maintenance complex component 4
Other Description CDC21 homolog|DNA replication licensing factor MCM4|homolog of S. pombe cell devision cycle 21|minichromosome maintenance deficient 4
Swissprots Q8NEH1 P33991 Q99658
Accessions AAB51723 AAC52018 AAS83108 CBX85473 EAW86684 EAW86685 EAW86686 P33991 AK022899 BAG51132 AK296913 BAG59468 AK309812 AM493756 CAM35476 BC031061 AAH31061 BF793151 BM781972 BQ058022 BQ689703 X74794 CAA52801 XM_005251234 XP_005251291 NM_005914 NP_005905 NM_182746 NP_877423
Function Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity. {ECO:0000269|PubMed:9305914}.
Subcellular Location Nucleus {ECO:0000250}.
Top Pathways DNA replication, Cell cycle

Mouse/Human MCM4 ELISA Kit (Cell-Based ELISA) - LS-F2134 from LifeSpan Bioscience

Category ELISA Kit
Prices $450.00
Sizes 1 plate

Rabbit anti-MCM4 Antibody, Affinity Purified - PLA0062 from Sigma-Aldrich

Prices $323.50
Sizes 100 µl
<B>Immunohistochemistry</B><BR/>Rabbit Anti-MCM4 Antibody, Affinity Purified: <B>Cat. No. PLA0062</B>: Detection of Human and Mouse MCM4 by Immunohistochemistry. Sample: FFPE section of Human testicular seminoma (left) and Mouse squamous cell carcinoma (right). Antibody: Affinity purified Rabbit Anti-MCM4 (<B>Cat. No. PLA0062</B>) used at a dilution of 1:1,000 (1 μg/mL). Detection: DAB

Goat anti-MCM4 Antibody, Affinity Purified - PLA0039 from Sigma-Aldrich

Prices $323.50
Sizes 100 µl
<B>Immunohistochemistry</B><BR/>Goat Anti-MCM4 Antibody, Affinity Purified: <B>Cat. No. PLA0039</B>: Detection of Human MCM4 by Immunohistochemistry. Sample: FFPE section of Human ovarian carcinoma. Antibody: Affinity purified goat Anti-MCM4 (<B>Cat. No. PLA0039</B>) used at a dilution of 1:1,000 (1 μg/mL). Detection: DAB

MCM4 (Human) IP-WB Antibody Pair - H00004173-PW1 from Acris Antibodies

Category Antibody Pair
Prices $610.00
Sizes 1 set

MCM4 (Human) Matched Antibody Pair - H00004173-AP21 from Acris Antibodies

Category Antibody Pair
Prices $610.00
Sizes 1 set

MCM4 (Human) Matched Antibody Pair - H00004173-AP22 from Acris Antibodies

Category Antibody Pair
Prices $610.00
Sizes 1 set

MCM4 Colorimetric Cell-Based ELISA Kit - CB5434 from Assay Biotechnology

Category ELISA Kit
Prices $380.00, $760.00, $1,140.00
Sizes 1 kit, 2 kits, 3 kits
Range > 5000 Cells

MCM4 (Phospho-Ser54) Colorimetric Cell-Based ELISA Kit - CBP1363 from Assay Biotechnology

Category ELISA Kit
Prices $480.00, $960.00, $1,440.00
Sizes 1 kit, 2 kits, 3 kits
Range > 5000 Cells

minichromosome maintenance complex component 4, ELISA Kit - MBS9343244 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

MCM4 (Phospho-Ser54) ELISA Kit - DEIA-XYA1880 from Creative Diagnostics

Category ELISA Kit

Human MCM4 ELISA Kit - E024573 from Biobool

Category ELISA Kit

MCM4 Colorimetric Cell-Based ELISA Kit - EKA50369 from Biomatik

Category ELISA Kit
Prices $399.00
Sizes 96 tests
Sensitivity At least 5000 cells/well
Range Qualitative
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