| Gene Symbol |
PPP1R12C
|
| Entrez Gene |
54776
|
| Alt Symbol |
LENG3, MBS85, p84, p85
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
protein phosphatase 1, regulatory subunit 12C
|
| Other Description |
leukocyte receptor cluster (LRC) encoded novel gene 3|leukocyte receptor cluster (LRC) member 3|myosin-binding subunit 85|protein phosphatase 1 myosin-binding subunit of 85 kDa|protein phosphatase 1 myosin-binding subunit p85|protein phosphatase 1 regulatory subunit 12C|protein phosphatase 1, regulatory (inhibitor) subunit 12C
|
| Swissprots |
Q96HW1 Q7L8F7 Q9H5H5 B4DME2 Q9NT00 Q6ZPD1 Q59FK8 Q9BZL4
|
| Accessions |
EAW72332 EAW72333 EAW72334 EAW72335 Q9BZL4 AA551617 AB209452 BAD92689 AF211968 AF312028 AAG60045 AK027086 BAB15651 AK129529 BAC85179 AK297187 BAG59676 AK297426 BAG59854 AL137618 CAB70844 BC008030 AAH08030 BC010628 BC156295 AAI56296 HY013088 XM_005259013 XP_005259070 XM_011527045 XP_011525347 XR_935836 NM_001271618 NP_001258547 NM_017607 NP_060077
|
| Function |
Regulates myosin phosphatase activity. {ECO:0000269|PubMed:11399775}.
|
| Subcellular Location |
Cytoplasm {ECO:0000269|PubMed:11399775, ECO:0000269|PubMed:12923170}. Note=Along actomyosin filaments and stress fibers. {ECO:0000269|PubMed:11399775, ECO:0000269|PubMed:12923170}.
|
| Tissue Specificity |
Ubiquitously expressed. Highly expressed in heart. {ECO:0000269|PubMed:11399775}.
|
| Top Pathways |
Focal adhesion, Vascular smooth muscle contraction, Oxytocin signaling pathway, Proteoglycans in cancer, Regulation of actin cytoskeleton
|