Gene Symbol | PPP1R12C |
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Entrez Gene | 54776 |
Alt Symbol | LENG3, MBS85, p84, p85 |
Species | Human |
Gene Type | protein-coding |
Description | protein phosphatase 1, regulatory subunit 12C |
Other Description | leukocyte receptor cluster (LRC) encoded novel gene 3|leukocyte receptor cluster (LRC) member 3|myosin-binding subunit 85|protein phosphatase 1 myosin-binding subunit of 85 kDa|protein phosphatase 1 myosin-binding subunit p85|protein phosphatase 1 regulatory subunit 12C|protein phosphatase 1, regulatory (inhibitor) subunit 12C |
Swissprots | Q96HW1 Q7L8F7 Q9H5H5 B4DME2 Q9NT00 Q6ZPD1 Q59FK8 Q9BZL4 |
Accessions | EAW72332 EAW72333 EAW72334 EAW72335 Q9BZL4 AA551617 AB209452 BAD92689 AF211968 AF312028 AAG60045 AK027086 BAB15651 AK129529 BAC85179 AK297187 BAG59676 AK297426 BAG59854 AL137618 CAB70844 BC008030 AAH08030 BC010628 BC156295 AAI56296 HY013088 XM_005259013 XP_005259070 XM_011527045 XP_011525347 XR_935836 NM_001271618 NP_001258547 NM_017607 NP_060077 |
Function | Regulates myosin phosphatase activity. {ECO:0000269|PubMed:11399775}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:11399775, ECO:0000269|PubMed:12923170}. Note=Along actomyosin filaments and stress fibers. {ECO:0000269|PubMed:11399775, ECO:0000269|PubMed:12923170}. |
Tissue Specificity | Ubiquitously expressed. Highly expressed in heart. {ECO:0000269|PubMed:11399775}. |
Top Pathways | Focal adhesion, Vascular smooth muscle contraction, Oxytocin signaling pathway, Proteoglycans in cancer, Regulation of actin cytoskeleton |
PPP1R12C (H-150) - sc-366733 from Santa Cruz Biotechnology
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PPP1R12C (H-10) - sc-398415 from Santa Cruz Biotechnology
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Anti-PPP1R12C antibody - ab139703 from Abcam
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Anti-PPP1R12C antibody - ab126362 from Abcam
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Anti-PPP1R12C / MBS85 Antibody (aa571-620) - LS-C170028 from LifeSpan Bioscience
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PPP1R12C Antibody - NBP1-94079 from Novus Biologicals
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Anti-PPP1R12C antibody produced in rabbit - HPA043532 from Sigma-Aldrich
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PPP1R12C Antibody - middle region (ARP67757_P050) - ARP67757_P050 from Aviva Systems Biology
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PPP1R12C antibody - H00054776-B01P from Acris Antibodies
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Anti-PPP1R12C polyclonal antibody - DPAB12438 from Creative Diagnostics
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Anti-PPP1R12C (aa 571-620) polyclonal antibody - DPABH-02054 from Creative Diagnostics
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Anti-PPP1R12C (aa 148-233) polyclonal antibody - DPABH-22766 from Creative Diagnostics
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PPP1R12C-Antibody-middle-region-AI15529 - AI15529 from Abgent, a WuXi AppTec company
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PPP1R12C antibody - TA331892 from Acris Antibodies
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PPP1R12C antibody - orb326681 from Biorbyt
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PPP1R12C Antibody,Biotin conjugated - CSB-PA871627LD01HU from Cusabio
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PPP1R12C Antibody,FITC conjugated - CSB-PA871627LC01HU from Cusabio
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PPP1R12C Antibody,HRP conjugated - CSB-PA871627LB01HU from Cusabio
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PPP1R12C Antibody - CSB-PA871627LA01HU from Cusabio
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Anti-PPP1R12C Antibody A09178 - A09178 from Boster Bio
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PPP1R12C Antibody - middle region : Biotin (ARP67757_P050-Biotin) - ARP67757_P050-Biotin from Aviva Systems Biology
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PPP1R12C Antibody - middle region : FITC (ARP67757_P050-FITC) - ARP67757_P050-FITC from Aviva Systems Biology
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PPP1R12C Antibody - middle region : HRP (ARP67757_P050-HRP) - ARP67757_P050-HRP from Aviva Systems Biology
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Anti-PPP1R12C / MBS85 Antibody (HRP) - LS-C501827 from LifeSpan Bioscience
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Anti-PPP1R12C / MBS85 Antibody (FITC) - LS-C501823 from LifeSpan Bioscience
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