Camk4

Gene Symbol Camk4
Entrez Gene 12326
Alt Symbol A430110E23Rik, AI666733, CaMKIV, CaMKIV/Gr, D18Bwg0362e
Species Mouse
Gene Type protein-coding
Description calcium/calmodulin-dependent protein kinase IV
Other Description CAM kinase-GR|Ca2+/calmodulin-dependent protein kinase type IV/Gr|caMK IV|calcium/calmodulin-dependent protein kinase type IV
Swissprots P08414 Q61381
Accessions EDK97068 EDK97069 P08414 AK030219 BAC26850 AK030817 AK040523 AK043114 BAC31462 AK043457 AK079904 AK148809 BC070420 AAH70420 CJ104330 J03057 AAA37366 M16206 AAA39933 M64266 AAA37364 X58995 CAA41741 XM_006525543 XP_006525606 XM_006525544 XP_006525607 XM_006525546 XP_006525609 XM_006525547 XP_006525610 XR_877121 NM_009793 NP_033923
Function Calcium/calmodulin-dependent protein kinase that operates in the calcium-triggered CaMKK-CaMK4 signaling cascade and regulates, mainly by phosphorylation, the activity of several transcription activators, such as CREB1, MEF2D, JUN and RORA, which play pivotal roles in immune response, inflammation, and memory consolidation. In the thymus, regulates the CD4(+)/CD8(+) double positive thymocytes selection threshold during T-cell ontogeny. In CD4 memory T-cells, is required to link T-cell antigen receptor (TCR) signaling to the production of IL2, IFNG and IL4 (through the regulation of CREB and MEF2). Regulates the differentiation and survival phases of osteoclasts and dendritic cells (DCs). Mediates DCs survival by linking TLR4 and the regulation of temporal expression of BCL2. Phosphorylates the transcription activator CREB1 on 'Ser-133' in hippocampal neuron nuclei and contribute to memory consolidation and long term potentiation (LTP) in the hippocampus. Can activate the MAP kinases MA
Subcellular Location Cytoplasm {ECO:0000269|PubMed:10932193}. Nucleus {ECO:0000269|PubMed:10932193}. Note=Localized in hippocampal neuron nuclei (By similarity). In spermatids, associated with chromatin and nuclear matrix. {ECO:0000250}.
Tissue Specificity Expressed in brain and testis. {ECO:0000269|PubMed:10932193, ECO:0000269|PubMed:11951046}.
Top Pathways cAMP signaling pathway, Long-term potentiation, Oxytocin signaling pathway, Alcoholism, Amphetamine addiction

Mouse-Camk4-Antibody-C-term-Blocking-Peptide - BP16069b from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg
Species Mouse

Mouse CAMK4 protein (GST Tag) - orb138303 from Biorbyt

Category Protein
Prices $323.00, $646.00
Sizes 20 μg, 100 μg
Source Baculovirus-Insect Cells
Species Mouse
SDS-PAGE analysis of mouse CAMK4 protein (GST Tag)

Mouse CAMK4 protein - orb138304 from Biorbyt

Category Protein
Prices $323.00, $646.00
Sizes 20 μg, 100 μg
Source Baculovirus-Insect Cells
Species Mouse
SDS-PAGE analysis of mouse CAMK4 protein

Recombinant Mouse Camk4, His & GST tagged - Camk4-7403M from Creative Biomart

Category Protein
Source Baculovirus-Insect Cells
Species Mouse

Recombinant Mouse Camk4, Gly & Pro tagged - Camk4-477M from Creative Biomart

Category Protein
Source Baculovirus-Insect cells
Species Mouse

Mouse CAMK4 / CaMKIV Protein - 50838-MNCB-20 from Sino Biological

Category Protein
Source Baculovirus-Insect Cells
Species Mouse

Mouse CAMK4 / CaMKIV Protein (His & GST Tag) - 50838-M20B-100 from Sino Biological

Category Protein
Source Baculovirus-Insect Cells
Species Mouse

Recombinant Mouse Calcium/calmodulin-dependent protein kinase type IV(Camk4) - CSB-YP004471MO CSB-EP004471MO CSB-BP004471MO CSB-MP004471MO from Cusabio

Category Protein
Source Yeast or E.coli or Baculovirus or Mammalian cell
Species Mouse

Calcium/calmodulin-dependent protein kinase type IV (Camk4), Recombinant Protein - MBS951765 from MyBioSource

Category Protein
Prices $1,250.00, $1,250.00, $1,470.00, $1,470.00, $2,040.00, $2,040.00, $2,505.00, $2,505.00
Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell)
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Mouse

Recombinant Mouse CAMK4 / CaMKIV Protein - PKSM040459 from Elabscience

Category Protein
Source Baculoviru
Species Mouse

Recombinant Mouse CAMK4 / CaMKIV Protein (His & GST tag) - PKSM040460 from Elabscience

Category Protein
Source Baculoviru
Species Mouse

Mouse CAMK4 / CaMKIV Protein (His & GST Tag) - 50838-M20B-50 from Sino Biological

Category Protein
Source Baculovirus-Insect Cells
Species Mouse

Mouse CAMK4 / CaMKIV Protein - 50838-MNCB-50 from Sino Biological

Category Protein
Source Baculovirus-Insect Cells
Species Mouse

Mouse CAMK4 / CaMKIV Protein (His & GST Tag) - 50838-M20B from ABclonal

Category Protein
Prices $138.00, $198.00
Sizes 20 µg, 50 µg
Source Baculovirus-Insect Cells
Species Mouse

Mouse CAMK4 / CaMKIV Protein - 50838-MNCB from ABclonal

Category Protein
Prices $198.00, $258.00
Sizes 20 µg, 50 µg
Source Baculovirus-Insect Cells
Species Mouse

CAMK4 / CaMKIV, Recombinant Protein - MBS2546762 from MyBioSource

Category Protein
Prices $525.00, $675.00
Sizes 20 µg, 50 µg
Source Baculovirus-Insect Cells

CAMK4 / CaMKIV, Recombinant Protein - MBS2546763 from MyBioSource

Category Protein
Prices $375.00, $525.00
Sizes 20 µg, 50 µg
Source Baculovirus-Insect Cells
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