Camk4

Gene Symbol Camk4
Entrez Gene 12326
Alt Symbol A430110E23Rik, AI666733, CaMKIV, CaMKIV/Gr, D18Bwg0362e
Species Mouse
Gene Type protein-coding
Description calcium/calmodulin-dependent protein kinase IV
Other Description CAM kinase-GR|Ca2+/calmodulin-dependent protein kinase type IV/Gr|caMK IV|calcium/calmodulin-dependent protein kinase type IV
Swissprots P08414 Q61381
Accessions EDK97068 EDK97069 P08414 AK030219 BAC26850 AK030817 AK040523 AK043114 BAC31462 AK043457 AK079904 AK148809 BC070420 AAH70420 CJ104330 J03057 AAA37366 M16206 AAA39933 M64266 AAA37364 X58995 CAA41741 XM_006525543 XP_006525606 XM_006525544 XP_006525607 XM_006525546 XP_006525609 XM_006525547 XP_006525610 XR_877121 NM_009793 NP_033923
Function Calcium/calmodulin-dependent protein kinase that operates in the calcium-triggered CaMKK-CaMK4 signaling cascade and regulates, mainly by phosphorylation, the activity of several transcription activators, such as CREB1, MEF2D, JUN and RORA, which play pivotal roles in immune response, inflammation, and memory consolidation. In the thymus, regulates the CD4(+)/CD8(+) double positive thymocytes selection threshold during T-cell ontogeny. In CD4 memory T-cells, is required to link T-cell antigen receptor (TCR) signaling to the production of IL2, IFNG and IL4 (through the regulation of CREB and MEF2). Regulates the differentiation and survival phases of osteoclasts and dendritic cells (DCs). Mediates DCs survival by linking TLR4 and the regulation of temporal expression of BCL2. Phosphorylates the transcription activator CREB1 on 'Ser-133' in hippocampal neuron nuclei and contribute to memory consolidation and long term potentiation (LTP) in the hippocampus. Can activate the MAP kinases MA
Subcellular Location Cytoplasm {ECO:0000269|PubMed:10932193}. Nucleus {ECO:0000269|PubMed:10932193}. Note=Localized in hippocampal neuron nuclei (By similarity). In spermatids, associated with chromatin and nuclear matrix. {ECO:0000250}.
Tissue Specificity Expressed in brain and testis. {ECO:0000269|PubMed:10932193, ECO:0000269|PubMed:11951046}.
Top Pathways cAMP signaling pathway, Long-term potentiation, Oxytocin signaling pathway, Alcoholism, Amphetamine addiction

Anti-CAMKIV antibody - ab31970 from Abcam

Prices $359.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-CAMK4 antibody produced in rabbit - AV37025 from Sigma-Aldrich

Prices $267.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Cell Type: thymus (<B>Cat. No. AV37025</B>).<BR/><B>Lanes</B><BR/>1. Antibody dilution (concentration) 2.5 μg/mL in cell type thymus

CAMK4 antibody - C-terminal region (ARP37025_T100) - ARP37025_T100 from Aviva Systems Biology

Prices $229.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Camk4 Antibody - C-terminal region (ARP37026_P050) - ARP37026_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Mouse-Camk4-Antibody-C-term - AP16069b from Abgent, a WuXi AppTec company

Prices $99.00, $295.00
Sizes 80 µl, 400 µl
Host Rabbit
Clonality Polyclonal
Mouse Camk4 Antibody (C-term) (Cat. #AP16069b) western blot analysis in mouse heart tissue lysates (35ug/lane).This demonstrates the Camk4 antibody detected the Camk4 protein (arrow).

Mouse Camk4 Antibody - C-terminal region (OAAB11469) - OAAB11469 from Aviva Systems Biology

Prices $289.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal

CaMK4 antibody (Thr196/200) - 70R-33454 from Fitzgerald

Prices $275.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti -Camk4, CT (Camk4, Calcium/calmodulin-dependent protein kinase type IV, CaMkinase-GR) - 033166 from USBiological Life Science

Host Rabbit
Clonality Polyclonal

CaMK4 antibody - 70R-33455 from Fitzgerald

Prices $275.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

CAMK4 antibody - 20R-1131 from Fitzgerald

Prices $290.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Mouse Camk4 Antibody - abx028576 from Abbexa

Host Rabbit
Clonality Polyclonal

CAMK4 Antibody - 28-608 from ProSci

Prices $250.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Antibody used in WB on Human Thymus at 2.5 ug/ml.

CAMK4 Antibody - GWB-6F571C from Genway Biotech

Prices $294.00
Sizes 100 µg
Clonality Polyclonal

CAMK4, Polyclonal Antibody - MBS833627 from MyBioSource

Prices $390.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

CAMK4 / CaMKIV Antibody, Rabbit PAb - 50838-RP01-200 from Sino Biological

Prices $230.00, $230.00
Sizes 100 µg, 200 µg
Host Rabbit
Clonality Polyclonal

CAMK4 / CaMKIV Antibody, Rabbit PAb, Antigen Affinity Purified - 50838-RP02-50 from Sino Biological

Prices $170.00, $290.00
Sizes 50 µg, 100 µg
Host Rabbit
Clonality Polyclonal

CaM Kinase 4 / CaMKIV Antibody, Rabbit MAb - 50838-R162-50 from Sino Biological

Prices $170.00, $290.00
Sizes 50 µg, 100 µg
Host Rabbit
Clonality Monoclonal
Clone 162

CaM Kinase 4 / CaMKIV Antibody, Rabbit MAb - 50838-R001-100 from Sino Biological

Prices $170.00, $290.00
Sizes 50 µg, 100 µg
Host Rabbit
Clonality Monoclonal
Clone 001

Camk4-Antibody-C-terminal-region-AI11104 - AI11104 from Abgent, a WuXi AppTec company

Prices $293.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Host: Rabbit Target Name: Camk4 Sample Tissue: Mouse Testis lysates Antibody Dilution: 1.0ug/ml
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