Gene Symbol | BEST3 |
---|---|
Entrez Gene | 144453 |
Alt Symbol | VMD2L3 |
Species | Human |
Gene Type | protein-coding |
Description | bestrophin 3 |
Other Description | bestrophin-3|vitelliform macular dystrophy 2-like 3|vitelliform macular dystrophy 2-like protein 3 |
Swissprots | Q8N356 Q53YQ7 B5MDI8 Q9BR80 F8VVZ2 Q8N1M1 Q8NFT9 |
Accessions | EAW97232 EAW97233 EAW97234 EAW97235 Q8N1M1 AF440758 AAM76997 AK096459 BAC04797 AY515706 AAR99656 BC006440 AAH06440 BC028087 BC151138 BC166663 AAI66663 BF739974 BP225850 BX374313 DA767581 XM_005268674 XP_005268731 XM_006719252 XP_006719315 XM_006719256 XP_006719319 XM_011537961 XP_011536263 XM_011537962 XP_011536264 XM_011537963 XP_011536265 XM_011537964 XP_011536266 XM_011537965 XP_011536267 NM_001282613 NP_001269542 NM_001282614 NP_001269543 NM_001282615 NP_001269544 NM_001282616 NP_001269545 NM_032735 NP_116124 NM_152439 NP_689652 NR_104220 |
Function | Forms calcium-sensitive chloride channels. Permeable to bicarbonate. {ECO:0000269|PubMed:12907679}. |
Subcellular Location | Cell membrane; Multi-pass membrane protein. |
Tissue Specificity | Present in skeletal muscle and weakly in brain, spinal cord, bone marrow and retina. {ECO:0000269|PubMed:12032738}. |