| Gene Symbol |
BEST3
|
| Entrez Gene |
144453
|
| Alt Symbol |
VMD2L3
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
bestrophin 3
|
| Other Description |
bestrophin-3|vitelliform macular dystrophy 2-like 3|vitelliform macular dystrophy 2-like protein 3
|
| Swissprots |
Q8N356 Q53YQ7 B5MDI8 Q9BR80 F8VVZ2 Q8N1M1 Q8NFT9
|
| Accessions |
EAW97232 EAW97233 EAW97234 EAW97235 Q8N1M1 AF440758 AAM76997 AK096459 BAC04797 AY515706 AAR99656 BC006440 AAH06440 BC028087 BC151138 BC166663 AAI66663 BF739974 BP225850 BX374313 DA767581 XM_005268674 XP_005268731 XM_006719252 XP_006719315 XM_006719256 XP_006719319 XM_011537961 XP_011536263 XM_011537962 XP_011536264 XM_011537963 XP_011536265 XM_011537964 XP_011536266 XM_011537965 XP_011536267 NM_001282613 NP_001269542 NM_001282614 NP_001269543 NM_001282615 NP_001269544 NM_001282616 NP_001269545 NM_032735 NP_116124 NM_152439 NP_689652 NR_104220
|
| Function |
Forms calcium-sensitive chloride channels. Permeable to bicarbonate. {ECO:0000269|PubMed:12907679}.
|
| Subcellular Location |
Cell membrane; Multi-pass membrane protein.
|
| Tissue Specificity |
Present in skeletal muscle and weakly in brain, spinal cord, bone marrow and retina. {ECO:0000269|PubMed:12032738}.
|
![Western Blot: Bestrophin 3 Overexpression Lysate (Adult Normal) [NBP2-05368] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for Bestrophin 3.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_1/17411_Bestrophin%25203%2520Overexpression%2520Lysate%2520%2528Adult%2520Normal%2529-Western%2520Blot-NBP2-05368-img0001.jpg)