TAF4B

Gene Symbol	TAF4B
Entrez Gene	6875
Alt Symbol	SPGF13, TAF2C2, TAFII105
Species	Human
Gene Type	protein-coding
Description	TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
Other Description	TAF(II)105|TATA box binding protein (TBP)-associated factor 4B|TATA box binding protein (TBP)-associated factor, RNA polymerase II, C2, 105kD|transcription initiation factor TFIID 105 kDa subunit|transcription initiation factor TFIID subunit 4B
Swissprots	Q29YA5 Q29YA4 Q92750
Accessions	BAF51562 CCO13829 EAX01217 EAX01218 Q92750 AB234096 BAF51561 AK302593 BAG63845 AY888048 AAX14897 AY888049 AAX14898 BC016360 BC032791 BC169304 BC169305 Y09321 CAA70499 XM_005258339 XP_005258396 XM_006722528 XP_006722591 XM_011526153 XP_011524455 NM_001293725 NP_001280654 NM_005640 NP_005631 NR_121653
Function	Cell type-specific subunit of the general transcription factor TFIID that may function as a gene-selective coactivator in certain cells. TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors. TAF4B is a transcriptional coactivator of the p65/RELA NF-kappa-B subunit. Involved in the activation of a subset of antiapoptotic genes including TNFAIP3. May be involved in regulating folliculogenesis. Through interaction with OCBA/POU2AF1, acts as a coactivator of B-cell-specific transcription. Plays a role in spermiogenesis and oogenesis. {ECO:0000250|UniProtKB:G5E8Z2, ECO:0000269|PubMed:10828057, ECO:0000269|PubMed:10849440, ECO:0000269|PubMed:16088961, ECO:0000303|PubMed:24431330}.
Subcellular Location	Nucleus. Cytoplasm. Note=Export into the cytoplasm is mediated by a CRM1-independent nuclear export pathway and not by phosphorylation.
Tissue Specificity	Preferentially expressed in ovarian granulosa cells (at protein level). Highly expressed in B-cells. {ECO:0000269|PubMed:16088961, ECO:0000269|PubMed:8858156}.
Top Pathways	Huntington's disease, Herpes simplex infection, Basal transcription factors

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

TAF II p105 (N-16) - sc-85178 from Santa Cruz Biotechnology Prices $279.00 Sizes 100 µg/ml Host Rabbit Clonality Polyclonal

TAF II p105 (K-15) - sc-85177 from Santa Cruz Biotechnology Prices $279.00 Sizes 100 µg/ml Host Rabbit Clonality Polyclonal

TAF II p105 (TAFAD26A) - sc-81122 from Santa Cruz Biotechnology Prices $295.00 Sizes 100 µg/ml Host Mouse Clonality Monoclonal

Anti-TAF4B antibody - ab110510 from Abcam Prices $370.00 Sizes 400 µl Host Rabbit Clonality Polyclonal

Anti-TAF4B antibody [TAFAD26A] - ab50808 from Abcam Prices $370.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone TAFAD26A

Anti-TAF4B antibody - C-terminal - ab189428 from Abcam Prices $370.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-TAF4B Antibody (aa647-675) IHC-plus™ - LS-B9327 from LifeSpan Bioscience Prices $395.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-TAF4B Antibody - LS-C76197 from LifeSpan Bioscience Prices $365.00 Sizes 50 µg Host Mouse Clonality Monoclonal

Anti-TAF4B Antibody (aa654-683, AP) - LS-C270978 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-TAF4B Antibody (aa654-683, APC) - LS-C270979 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-TAF4B Antibody (aa654-683, Azide-free, HRP) - LS-C270982 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-TAF4B Antibody (aa654-683, Biotin) - LS-C270980 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-TAF4B Antibody (aa654-683, FITC) - LS-C270981 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-TAF4B Antibody (aa654-683, PE) - LS-C270983 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-TAF4B Antibody (aa654-683) - LS-C325558 from LifeSpan Bioscience Prices $345.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-TAF4B Antibody (clone TAFAD26A) - LS-C184269 from LifeSpan Bioscience Prices $335.00 Sizes 50 µg Host Mouse Clonality Monoclonal Clone TAFAD26A

Anti-TAF4B Antibody (aa211-260) - LS-C206174 from LifeSpan Bioscience Prices $365.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

Anti-TAF4B Antibody (clone TAFAD26A) - LS-C342327 from LifeSpan Bioscience Prices $375.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone TAFAD26A

TAF4B Antibody - NBP1-90657 from Novus Biologicals Prices $419.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-TAF4B antibody produced in rabbit - HPA028937 from Sigma-Aldrich Prices $429.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

TAF4B Antibody - N-terminal region (ARP72855_P050) - ARP72855_P050 from Aviva Systems Biology Prices $289.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

TAF4B-Antibody-C-term - AP12163b from Abgent, a WuXi AppTec company Prices $99.00, $295.00 Sizes 80 µl, 400 µl Host Rabbit Clonality Polyclonal

TAF4B Antibody - C-terminal region (OAAB08404) - OAAB08404 from Aviva Systems Biology Prices $289.00 Sizes 400 µl Host Rabbit Clonality Polyclonal

TAF4B antibody - 10R-1231 from Fitzgerald Prices $190.00 Sizes 50 µg Host Mouse Clonality Monoclonal Clone TAFAD26A

TAF4B Antibody - abx026627 from Abbexa Host Rabbit Clonality Polyclonal

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