KDSR

Gene Symbol	KDSR
Entrez Gene	2531
Alt Symbol	DHSR, FVT1, SDR35C1
Species	Human
Gene Type	protein-coding
Description	3-ketodihydrosphingosine reductase
Other Description	3-dehydrosphinganine reductase|FVT-1|KDS reductase|follicular lymphoma variant translocation 1|follicular variant translocation protein 1|short chain dehydrogenase/reductase family 35C member 1|short chain dehydrogenase/reductase family 35C, member 1
Swissprots	B2R5Y1 Q06136 B4DMX0
Accessions	EAW63140 EAW63141 Q06136 AF086045 AK025120 AK093874 AK126679 AK297670 BAG60032 AK312360 BAG35278 BC008797 AAH08797 BI458411 BT006782 AAP35428 X63657 CAA45197 XM_005266677 XP_005266734 XM_006722433 XP_006722496 NM_002035 NP_002026
Function	Catalyzes the reduction of 3-ketodihydrosphingosine (KDS) to dihydrosphingosine (DHS).
Subcellular Location	Endoplasmic reticulum membrane {ECO:0000269|PubMed:15328338}; Multi-pass membrane protein {ECO:0000269|PubMed:15328338}.
Tissue Specificity	Expressed in all tissues examined. Highest expression in placenta. High expression in lung, kidney, stomach and small intestine, low expression in heart, spleen and skeletal muscle. Weakly expressed in normal hematopoietic tissues. Higher expression in some T-cell malignancies and PHA-stimulated lymphocytes.
Top Pathways	Sphingolipid metabolism

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human FVT1 protein fragment - ab104822 from Abcam Category Protein Source E. coli Species Human

Human FVT1 protein fragment - ab125172 from Abcam Category Protein Source E. coli Species Human

FVT1 Recombinant Protein - H00002531-P02 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

FVT1 Recombinant Protein - H00002531-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human FVT1 Protein - NBP1-51022 from Novus Biologicals Category Protein Prices $269.00, $729.00 Sizes 100 µg, 500 µg Source E. coli Species Human

KDSR Protein (OOPA00108) - OOPA00108 from Aviva Systems Biology Category Protein Prices $100.00 Sizes 5 µg Source Escherichia Coli.

Human KDSR protein - orb168691 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 5 μg, 20 μg Source E. coli

KDSR protein (His tag) - 80R-1706 from Fitzgerald Category Protein Prices $255.00 Sizes 100 µg Source E.coli

KDS reductase (26-270, His-tag) - AR09888PU-L from Acris Antibodies Category Protein Prices $790.00 Sizes 500 µg Source E. coli Species Human

KDS reductase (26-270, His-tag) - AR09888PU-N from Acris Antibodies Category Protein Prices $340.00 Sizes 100 µg Source E. coli Species Human

KDS reductase - H00002531-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

KDS reductase - H00002531-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

KDS reductase - H00002531-P02 from Acris Antibodies Category Protein Prices $370.00 Sizes 10 µg Species Human

KDS reductase - H00002531-P02-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

KDS reductase - H00002531-P02-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

3-Ketodihydrosphingosine Reductase, Human Recombinant - 228-12244-1 from RayBiotech Category Protein Prices $118.00 Sizes 1 µg Source Escherichia Coli. Species Human

Recombinant 3-Ketodihydrosphingosine Reductase Human - 228-12244-2 from RayBiotech Category Protein Prices $189.00 Sizes 2 µg Source Escherichia Coli. Species Human

Recombinant 3-Ketodihydrosphingosine Reductase Human - 228-12244-3 from RayBiotech Category Protein Prices $2,880.00 Sizes 3 µg Source Escherichia Coli. Species Human

KDSR, 26-270aa, Human, His tag, E.coli - 01-P0948 from ARP American Research Products Category Protein Prices $179.00, $369.00, $849.00 Sizes 20 µg, 100 µg, 500 µg Species Human

KDSR fusion protein - Ag8176 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

KDSR fusion protein - Ag8198 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

KDSR Human - ENPS-099 from NeoScientific Category Protein Prices $65.00, $169.00, $3,510.00 Sizes 5 µg, 20 µg, 1 mg Source Escherichia Coli. Species Human

Recombinant Human 3-Ketodihydrosphingosine Reductase - BP000876-ENZ-092 from Syd Labs Category Protein Prices $160.00, $2,700.00 Sizes 20 µg, 1 mg Source E. coli-derived. Species Human

KDSR Human Protein - GWB-BSP220 from Genway Biotech Category Protein Prices $75.00, $165.00, $3,230.00 Sizes 5 μg, 20 μg, 1000 μg Source Escherichia Coli. Species Human

KDSR, 26-270aa, Recombinant Protein - GWB-P1090K from Genway Biotech Category Protein Prices $300.00, $900.00 Sizes 100 μg, 500 μg Source E.coli Species Human

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