KDSR

Gene Symbol	KDSR
Entrez Gene	2531
Alt Symbol	DHSR, FVT1, SDR35C1
Species	Human
Gene Type	protein-coding
Description	3-ketodihydrosphingosine reductase
Other Description	3-dehydrosphinganine reductase|FVT-1|KDS reductase|follicular lymphoma variant translocation 1|follicular variant translocation protein 1|short chain dehydrogenase/reductase family 35C member 1|short chain dehydrogenase/reductase family 35C, member 1
Swissprots	B2R5Y1 Q06136 B4DMX0
Accessions	EAW63140 EAW63141 Q06136 AF086045 AK025120 AK093874 AK126679 AK297670 BAG60032 AK312360 BAG35278 BC008797 AAH08797 BI458411 BT006782 AAP35428 X63657 CAA45197 XM_005266677 XP_005266734 XM_006722433 XP_006722496 NM_002035 NP_002026
Function	Catalyzes the reduction of 3-ketodihydrosphingosine (KDS) to dihydrosphingosine (DHS).
Subcellular Location	Endoplasmic reticulum membrane {ECO:0000269|PubMed:15328338}; Multi-pass membrane protein {ECO:0000269|PubMed:15328338}.
Tissue Specificity	Expressed in all tissues examined. Highest expression in placenta. High expression in lung, kidney, stomach and small intestine, low expression in heart, spleen and skeletal muscle. Weakly expressed in normal hematopoietic tissues. Higher expression in some T-cell malignancies and PHA-stimulated lymphocytes.
Top Pathways	Sphingolipid metabolism

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human KDSR Gene cDNA Clone - orb143955 from Biorbyt Prices $255.00 Sizes 10 μg Species Human

Human-KDSR-cDNA-Clone - DC02493 from Abgent, a WuXi AppTec company Prices $448.20 Sizes 10 µg Species Human Accession BC008797

KDSR - MBS1271748 from MyBioSource Prices $175.00 Sizes 10ug plasmid + 200ul glycerol stock Species Human Accession BC008797

Human KDSR/FVT1 Gene ORF cDNA clone in cloning vector - HG13516-G from Sino Biological Species Human

Human KDSR/FVT1 Gene ORF cDNA clone expression plasmid, N-Flag tag - HG13516-NF from Sino Biological Species Human

Human KDSR/FVT1 Gene ORF cDNA clone expression plasmid, N-Myc tag - HG13516-NM from Sino Biological Species Human

Human KDSR/FVT1 Gene ORF cDNA clone expression plasmid, C-Flag tag - HG13516-CF from Sino Biological Species Human

Human KDSR/FVT1 Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG13516-ACG from Sino Biological Species Human

Human KDSR/FVT1 Gene ORF cDNA clone expression plasmid, C-Myc tag - HG13516-CM from Sino Biological Species Human

Human KDSR/FVT1 Gene ORF cDNA clone expression plasmid, C-HA tag - HG13516-CY from Sino Biological Species Human

Human KDSR/FVT1 Gene ORF cDNA clone expression plasmid, N-His tag - HG13516-NH from Sino Biological Species Human

Human KDSR/FVT1 Gene ORF cDNA clone expression plasmid - HG13516-UT from Sino Biological Species Human

Human KDSR/FVT1 Gene ORF cDNA clone expression plasmid, C-His tag - HG13516-CH from Sino Biological Species Human

Human KDSR/FVT1 Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG13516-ACR from Sino Biological Species Human

Human KDSR/FVT1 Gene ORF cDNA clone expression plasmid, N-HA tag - HG13516-NY from Sino Biological Species Human

Human KDSR ORF Clone (BC008797) - CDCS410571 from Creative biogene Species Human Accession Q06136

Human KDSR ORF clone (BC008797) - CDCB159919 from Creative biogene Species Human

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