TNFRSF18

Gene Symbol TNFRSF18
Entrez Gene 8784
Alt Symbol AITR, CD357, GITR, GITR-D
Species Human
Gene Type protein-coding
Description tumor necrosis factor receptor superfamily, member 18
Other Description TNF receptor superfamily activation-inducible protein|activation-inducible TNFR family receptor|glucocorticoid-induced TNFR-related protein|tumor necrosis factor receptor superfamily member 18
Swissprots B1AME1 Q9NYJ9 Q5U0I4 O95851 Q9Y5U5
Accessions EAW56282 EAW56283 EAW56284 Q9Y5U5 AF117297 AAD19694 AF125304 AAD22635 AF241229 AAF63506 AY358877 AAQ89236 BC152381 AAI52382 BC152386 AAI52387 BC156102 AAI56103 BC156964 AAI56965 BE244247 BT019531 AAV38338 BT019532 AAV38339 NM_004195 NP_004186 NM_148901 NP_683699 NM_148902 NP_683700
Function Receptor for TNFSF18. Seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. Mediated NF-kappa-B activation via the TRAF2/NIK pathway.
Subcellular Location Isoform 1: Cell membrane; Single-pass type I membrane protein.
Tissue Specificity Expressed in lymph node, peripheral blood leukocytes and weakly in spleen.
Top Pathways Cytokine-cytokine receptor interaction

GITR CRISPR/Cas9 KO Plasmid (h) - sc-404899 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

GITR HDR Plasmid (h) - sc-404899-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

GITR Double Nickase Plasmid (h) - sc-404899-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

GITR Double Nickase Plasmid (h2) - sc-404899-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

GITR CRISPR Activation Plasmid (h) - sc-404899-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

GITR CRISPR Activation Plasmid (h2) - sc-404899-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

GITR Lentiviral Activation Particles (h) - sc-404899-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

GITR Lentiviral Activation Particles (h2) - sc-404899-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

GITR siRNA (h) - sc-43806 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

GITR shRNA Plasmid (h) - sc-43806-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

GITR shRNA (h) Lentiviral Particles - sc-43806-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

GITR/TNFRSF18 RNAi - H00008784-R01V from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

GITR/TNFRSF18 RNAi - H00008784-R05 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

GITR/TNFRSF18 RNAi - H00008784-R04 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

GITR/TNFRSF18 RNAi - H00008784-R06 from Novus Biologicals

Category siRNA
Prices $409.00
Sizes 20 nmol
Species Reactivities Human

CompoZr® Knockout ZFN Kit - CKOZFN21749 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND21749 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR02622 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr02622

TNFRSF18 siRNA (Human) - CRH5785 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

TNFRSF18 - MBS8201617 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human TNFRSF18 (NM_004195.2) - SHH431956 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human TNFRSF18(NM_148901.1) - SHL084350 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human TNFRSF18(NM_004195.2) - SHL084826 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human TNFRSF18(NM_148902.1) - SHL084844 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human TNFRSF18(NM_148901.1) - SHL084880 from Creative biogene

Category siRNA
Species Reactivities Human
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