Gene Symbol | TNFRSF18 |
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Entrez Gene | 8784 |
Alt Symbol | AITR, CD357, GITR, GITR-D |
Species | Human |
Gene Type | protein-coding |
Description | tumor necrosis factor receptor superfamily, member 18 |
Other Description | TNF receptor superfamily activation-inducible protein|activation-inducible TNFR family receptor|glucocorticoid-induced TNFR-related protein|tumor necrosis factor receptor superfamily member 18 |
Swissprots | B1AME1 Q9NYJ9 Q5U0I4 O95851 Q9Y5U5 |
Accessions | EAW56282 EAW56283 EAW56284 Q9Y5U5 AF117297 AAD19694 AF125304 AAD22635 AF241229 AAF63506 AY358877 AAQ89236 BC152381 AAI52382 BC152386 AAI52387 BC156102 AAI56103 BC156964 AAI56965 BE244247 BT019531 AAV38338 BT019532 AAV38339 NM_004195 NP_004186 NM_148901 NP_683699 NM_148902 NP_683700 |
Function | Receptor for TNFSF18. Seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. Mediated NF-kappa-B activation via the TRAF2/NIK pathway. |
Subcellular Location | Isoform 1: Cell membrane; Single-pass type I membrane protein. |
Tissue Specificity | Expressed in lymph node, peripheral blood leukocytes and weakly in spleen. |
Top Pathways | Cytokine-cytokine receptor interaction |
Human TNFRSF18 full length protein - ab160184 from Abcam
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Human TNFRSF18 protein fragment - ab160185 from Abcam
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Human TNFRSF18 protein fragment - ab198670 from Abcam
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Mouse TNFRSF18 protein fragment - ab185843 from Abcam
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TNFRSF18 / GITR Blocking Peptide - LS-E10657 from LifeSpan Bioscience
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TNFRSF18 / GITR Antibody Blocking Peptide - LS-E25183 from LifeSpan Bioscience
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GITR/TNFRSF18 Partial Recombinant Protein - H00008784-Q01 from Novus Biologicals
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GITR/TNFRSF18 Recombinant Protein - H00008784-P01 from Novus Biologicals
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GITR/TNFRSF18 Recombinant Protein - H00008784-G01 from Novus Biologicals
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Recombinant Mouse GITR/TNFRSF18 Fc Chimera, CF - 524-GR-050 from R&D Systems
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Recombinant Human GITR/TNFRSF18 Fc Chimera, CF - 689-GR-100 from R&D Systems
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Human TNFRSF18 protein - orb139776 from Biorbyt
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TNFRSF18 Blocking Peptide - 33R-5394 from Fitzgerald
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TNFRSF18 Blocking Peptide - 33R-5016 from Fitzgerald
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TNFRSF18 / GITR - H00008784-G01 from Acris Antibodies
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TNFRSF18 / GITR - H00008784-P01-10 from Acris Antibodies
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TNFRSF18 / GITR - H00008784-P01-25 from Acris Antibodies
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TNFRSF18 / GITR - H00008784-Q01-10 from Acris Antibodies
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TNFRSF18 / GITR - H00008784-Q01-25 from Acris Antibodies
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TNFRSF 18 Recombinant Protein - 96-354 from ProSci
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Recombinant Human TNFRSF18, Fc Chimera - TNFRSF18-1621H from Creative Biomart
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Recombinant Human TNFRSF18, Fc tagged - TNFRSF18-554H from Creative Biomart
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Recombinant Human TNFRSF18, Fc-tagged - TNFRSF18-275H from Creative Biomart
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Recombinant Human TNFRSF18, His-tagged - TNFRSF18-2090H from Creative Biomart
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Recombinant Glucocorticoid Induced Tumor Necrosis Factor Receptor (GITR) - RPB662Hu01 from Uscn Life Science Inc.
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