TNFRSF18

Gene Symbol TNFRSF18
Entrez Gene 8784
Alt Symbol AITR, CD357, GITR, GITR-D
Species Human
Gene Type protein-coding
Description tumor necrosis factor receptor superfamily, member 18
Other Description TNF receptor superfamily activation-inducible protein|activation-inducible TNFR family receptor|glucocorticoid-induced TNFR-related protein|tumor necrosis factor receptor superfamily member 18
Swissprots B1AME1 Q9NYJ9 Q5U0I4 O95851 Q9Y5U5
Accessions EAW56282 EAW56283 EAW56284 Q9Y5U5 AF117297 AAD19694 AF125304 AAD22635 AF241229 AAF63506 AY358877 AAQ89236 BC152381 AAI52382 BC152386 AAI52387 BC156102 AAI56103 BC156964 AAI56965 BE244247 BT019531 AAV38338 BT019532 AAV38339 NM_004195 NP_004186 NM_148901 NP_683699 NM_148902 NP_683700
Function Receptor for TNFSF18. Seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. Mediated NF-kappa-B activation via the TRAF2/NIK pathway.
Subcellular Location Isoform 1: Cell membrane; Single-pass type I membrane protein.
Tissue Specificity Expressed in lymph node, peripheral blood leukocytes and weakly in spleen.
Top Pathways Cytokine-cytokine receptor interaction

Human TNFRSF18 full length protein - ab160184 from Abcam

Category Protein
Source Wheat germ
Species Human
ab160184 on a 12.5% SDS-PAGE stained with Coomassie Blue.

Human TNFRSF18 protein fragment - ab160185 from Abcam

Category Protein
Source Wheat germ
Species Human
ab160185 on a 12.5% SDS-PAGE stained with Coomassie Blue.

Human TNFRSF18 protein fragment - ab198670 from Abcam

Category Protein
Source HEK 293 cells
Species Human
4-20% SDS-PAGE analysis of ab198670 (3 μg) with Coomassie staining. Note: This protein runs at a higher MW by SDS-PAGE due to glycosylation.

Mouse TNFRSF18 protein fragment - ab185843 from Abcam

Category Protein
Source Mammalian
Species Mouse

TNFRSF18 / GITR Blocking Peptide - LS-E10657 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

TNFRSF18 / GITR Antibody Blocking Peptide - LS-E25183 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

GITR/TNFRSF18 Partial Recombinant Protein - H00008784-Q01 from Novus Biologicals

Category Protein
Prices $369.00
Sizes 10 µg
Species Human

GITR/TNFRSF18 Recombinant Protein - H00008784-P01 from Novus Biologicals

Category Protein
Prices $369.00
Sizes 10 µg
Species Human

GITR/TNFRSF18 Recombinant Protein - H00008784-G01 from Novus Biologicals

Category Protein
Prices $579.00
Sizes 10 µg
Species Human

Recombinant Mouse GITR/TNFRSF18 Fc Chimera, CF - 524-GR-050 from R&D Systems

Category Protein
Source Mouse myeloma cell line, NS0-derived

Recombinant Human GITR/TNFRSF18 Fc Chimera, CF - 689-GR-100 from R&D Systems

Category Protein
Source Mouse myeloma cell line, NS0-derived

Human TNFRSF18 protein - orb139776 from Biorbyt

Category Protein
Prices $298.00, $400.00
Sizes 50 μg, 100 μg
Source Human Cells
Species Human
SDS-PAGE analysis of human TNFRSF18 protein

TNFRSF18 Blocking Peptide - 33R-5394 from Fitzgerald

Category Peptide
Prices $130.00
Sizes 100 µg

TNFRSF18 Blocking Peptide - 33R-5016 from Fitzgerald

Category Peptide
Prices $130.00
Sizes 100 µg

TNFRSF18 / GITR - H00008784-G01 from Acris Antibodies

Category Protein
Prices $550.00
Sizes 10 µg
Species Human

TNFRSF18 / GITR - H00008784-P01-10 from Acris Antibodies

Category Protein
Prices $380.00
Sizes 10 µg
Species Human

TNFRSF18 / GITR - H00008784-P01-25 from Acris Antibodies

Category Protein
Prices $500.00
Sizes 25 µg
Species Human

TNFRSF18 / GITR - H00008784-Q01-10 from Acris Antibodies

Category Protein
Prices $380.00
Sizes 10 µg
Source in vitro transl.
Species Human

TNFRSF18 / GITR - H00008784-Q01-25 from Acris Antibodies

Category Protein
Prices $500.00
Sizes 25 µg
Source in vitro transl.
Species Human

TNFRSF 18 Recombinant Protein - 96-354 from ProSci

Category Protein
Prices $425.00
Sizes 100 µg
Source HEK293 cells
Species Human
The purity of rh GITR /TNFRSF18 was determined by DTT-reduced (+) SDS-PAGE and staining overnight with Coomassie Blue.

Recombinant Human TNFRSF18, Fc Chimera - TNFRSF18-1621H from Creative Biomart

Category Protein
Source NSO Cells.

Recombinant Human TNFRSF18, Fc tagged - TNFRSF18-554H from Creative Biomart

Category Protein
Source Human Cells
Species Human

Recombinant Human TNFRSF18, Fc-tagged - TNFRSF18-275H from Creative Biomart

Category Protein
Source HEK293 Cells
Species Human

Recombinant Human TNFRSF18, His-tagged - TNFRSF18-2090H from Creative Biomart

Category Protein
Source Human Cells
Species Human

Recombinant Glucocorticoid Induced Tumor Necrosis Factor Receptor (GITR) - RPB662Hu01 from Uscn Life Science Inc.

Category Protein
Source E.coli
Species Human
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