Gene Symbol | TNFRSF18 |
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Entrez Gene | 8784 |
Alt Symbol | AITR, CD357, GITR, GITR-D |
Species | Human |
Gene Type | protein-coding |
Description | tumor necrosis factor receptor superfamily, member 18 |
Other Description | TNF receptor superfamily activation-inducible protein|activation-inducible TNFR family receptor|glucocorticoid-induced TNFR-related protein|tumor necrosis factor receptor superfamily member 18 |
Swissprots | B1AME1 Q9NYJ9 Q5U0I4 O95851 Q9Y5U5 |
Accessions | EAW56282 EAW56283 EAW56284 Q9Y5U5 AF117297 AAD19694 AF125304 AAD22635 AF241229 AAF63506 AY358877 AAQ89236 BC152381 AAI52382 BC152386 AAI52387 BC156102 AAI56103 BC156964 AAI56965 BE244247 BT019531 AAV38338 BT019532 AAV38339 NM_004195 NP_004186 NM_148901 NP_683699 NM_148902 NP_683700 |
Function | Receptor for TNFSF18. Seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. Mediated NF-kappa-B activation via the TRAF2/NIK pathway. |
Subcellular Location | Isoform 1: Cell membrane; Single-pass type I membrane protein. |
Tissue Specificity | Expressed in lymph node, peripheral blood leukocytes and weakly in spleen. |
Top Pathways | Cytokine-cytokine receptor interaction |
TNFRSF18 293T Cell Transient Overexpression Lysate(Denatured) - H00008784-T01 from Acris Antibodies
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TNFRSF18 overexpression lysate - LY407757 from Acris Antibodies
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TNFRSF18 overexpression lysate - LY418153 from Acris Antibodies
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TNFRSF18 overexpression lysate - LY430192 from Acris Antibodies
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TNFRSF18 293 Cell Lysate - 408470 from ABBIOTEC
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GITR/TNFRSF18 Overexpression Lysate (Denatured) - H00008784-T01 from Novus Biologicals
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GITR/TNFRSF18 Overexpression Lysate (Native) - NBL1-17152 from Novus Biologicals
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GITR/TNFRSF18 Overexpression Lysate (Native) - NBP2-05429 from Novus Biologicals
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TNFRSF18 Over-expression Lysate Product - GWB-6C14B8 from Genway Biotech
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Human GITR / TNFRSF18 HEK293 Cell Lysate (WB positive control) - 13643-H02HL-300 from Sino Biological
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Human GITR Human Cells Transfected Lysate (positive control) (denatured) - orb174528 from Biorbyt
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GITR/TNFRSF18 Overexpression Lysate (Denatured) - H00008784-T02 from Novus Biologicals
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Panoply™ Human TNFRSF18 Knockdown Stable Cell Line - CSC-DC016361 from Creative biogene
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