Gene Symbol | E2F2 |
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Entrez Gene | 1870 |
Alt Symbol | E2F-2 |
Species | Human |
Gene Type | protein-coding |
Description | E2F transcription factor 2 |
Other Description | transcription factor E2F2 |
Swissprots | Q14209 B2R9W1 Q7Z6H1 |
Accessions | AAM54044 EAW95055 EAW95056 EAW95057 EAW95058 Q14209 AF086395 AK092799 AK313939 BAG36658 BC007609 AAH07609 BC053676 AAH53676 BT019523 AAV38330 L22846 AAA16890 XM_005245748 XP_005245805 XM_005245749 XP_005245806 XM_011540868 XP_011539170 XM_011540869 XP_011539171 XM_011540870 XP_011539172 XM_011540871 XP_011539173 NM_004091 NP_004082 |
Function | Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC- 3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DRTF1/E2F complex functions in the control of cell-cycle progression from g1 to s phase. E2F2 binds specifically to RB1 in a cell-cycle dependent manner. |
Subcellular Location | Nucleus. |
Tissue Specificity | Highest level of expression is found in placenta, low levels are found in lung. Found as well in many immortalized cell lines derived from tumor samples. |
Top Pathways | MicroRNAs in cancer, Cell cycle, HTLV-I infection, Prostate cancer, Glioma |
E2F-2 (H-9) - sc-514477 from Santa Cruz Biotechnology
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E2F-2 (C-20) - sc-633 from Santa Cruz Biotechnology
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E2F-2 (CC1) - sc-69678 from Santa Cruz Biotechnology
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E2F-2 (L-20) - sc-632 from Santa Cruz Biotechnology
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E2F-2 (CC11) - sc-56663 from Santa Cruz Biotechnology
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E2F-2 (H-120) - sc-22821 from Santa Cruz Biotechnology
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E2F-2 (TFE-25) - sc-9967 from Santa Cruz Biotechnology
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E2F-2 (TFE22) - sc-56664 from Santa Cruz Biotechnology
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E2F-2 (SPM392) - sc-65556 from Santa Cruz Biotechnology
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Anti-E2F2 antibody - ab65222 from Abcam
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Anti-E2F2 antibody - ab123374 from Abcam
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Anti-E2F2 antibody - ab14292 from Abcam
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Anti-E2F2 antibody [2302C4a] - ab70731 from Abcam
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Anti-E2F2 antibody [CC11] - ab11838 from Abcam
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Anti-E2F2 antibody [EPR8622] - ab138515 from Abcam
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Anti-E2F2 antibody - C-terminal - ab191031 from Abcam
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Anti-E2F2 Antibody - LS-C65133 from LifeSpan Bioscience
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Anti-E2F2 Antibody - LS-C65132 from LifeSpan Bioscience
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Anti-E2F2 Antibody (N-Terminus) - LS-C50393 from LifeSpan Bioscience
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Anti-E2F2 Antibody (C-Terminus) - LS-C65135 from LifeSpan Bioscience
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Anti-E2F2 Antibody (N-Terminus) - LS-C188976 from LifeSpan Bioscience
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Anti-E2F2 Antibody (clone 2302C4a) - LS-C184647 from LifeSpan Bioscience
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Anti-E2F2 Antibody (aa265-297, AP) - LS-C256427 from LifeSpan Bioscience
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Anti-E2F2 Antibody (aa265-297, APC) - LS-C256428 from LifeSpan Bioscience
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Anti-E2F2 Antibody (aa265-297, Biotin) - LS-C256430 from LifeSpan Bioscience
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