Gene Symbol | DSCC1 |
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Entrez Gene | 79075 |
Alt Symbol | DCC1 |
Species | Human |
Gene Type | protein-coding |
Description | DNA replication and sister chromatid cohesion 1 |
Other Description | defective in sister chromatid cohesion 1 homolog|defective in sister chromatid cohesion protein 1 homolog|sister chromatid cohesion protein DCC1 |
Swissprots | Q969N5 Q9BVC3 |
Accessions | EAW91994 EAW91995 Q9BVC3 AK054585 BAB70767 AK058129 AK074355 AK315356 AW149121 AY358866 AAQ89225 BC001316 AAH01316 BC001531 AAH01531 DA346021 DQ891267 ABM82193 DQ894455 ABM85381 XM_005251065 XP_005251122 NM_024094 NP_076999 |
Function | Loads PCNA onto primed templates regulating velocity, spacing and restart activity of replication forks. May couple DNA replication to sister chromatid cohesion through regulation of the acetylation of the cohesin subunit SMC3. {ECO:0000269|PubMed:12766176, ECO:0000269|PubMed:19907496}. |
Subcellular Location | Nucleus {ECO:0000250}. |
DCC1 CRISPR/Cas9 KO Plasmid (h) - sc-413127 from Santa Cruz Biotechnology
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DCC1 HDR Plasmid (h) - sc-413127-HDR from Santa Cruz Biotechnology
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DCC1 Double Nickase Plasmid (h) - sc-413127-NIC from Santa Cruz Biotechnology
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DCC1 Double Nickase Plasmid (h2) - sc-413127-NIC-2 from Santa Cruz Biotechnology
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DCC1 CRISPR Activation Plasmid (h) - sc-413127-ACT from Santa Cruz Biotechnology
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DCC1 CRISPR Activation Plasmid (h2) - sc-413127-ACT-2 from Santa Cruz Biotechnology
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DCC1 Lentiviral Activation Particles (h) - sc-413127-LAC from Santa Cruz Biotechnology
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DCC1 Lentiviral Activation Particles (h2) - sc-413127-LAC-2 from Santa Cruz Biotechnology
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DCC1 siRNA (h) - sc-77856 from Santa Cruz Biotechnology
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DCC1 shRNA Plasmid (h) - sc-77856-SH from Santa Cruz Biotechnology
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DCC1 shRNA (h) Lentiviral Particles - sc-77856-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU021301 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN7500 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND7500 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR07529 from Sigma-Aldrich
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DSCC1 siRNA (Human) - CRJ2294 from Cohesion Biosciences
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DSCC1 - MBS8226005 from MyBioSource
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shRNA set against Human DSCC1 (NM_024094.2) - SHH281177 from Creative biogene
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Human DSCC1 siRNA - orb272795 from Biorbyt
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DSCC1 shRNA Plasmid (Human) - CHJ2294 from Cohesion Biosciences
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DSCC1 miRNA 3'UTR clone - MiUTR3H-12783 from Creative biogene
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