Gene Symbol |
DSCC1
|
Entrez Gene |
79075
|
Alt Symbol |
DCC1
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
DNA replication and sister chromatid cohesion 1
|
Other Description |
defective in sister chromatid cohesion 1 homolog|defective in sister chromatid cohesion protein 1 homolog|sister chromatid cohesion protein DCC1
|
Swissprots |
Q969N5 Q9BVC3
|
Accessions |
EAW91994 EAW91995 Q9BVC3 AK054585 BAB70767 AK058129 AK074355 AK315356 AW149121 AY358866 AAQ89225 BC001316 AAH01316 BC001531 AAH01531 DA346021 DQ891267 ABM82193 DQ894455 ABM85381 XM_005251065 XP_005251122 NM_024094 NP_076999
|
Function |
Loads PCNA onto primed templates regulating velocity, spacing and restart activity of replication forks. May couple DNA replication to sister chromatid cohesion through regulation of the acetylation of the cohesin subunit SMC3. {ECO:0000269|PubMed:12766176, ECO:0000269|PubMed:19907496}.
|
Subcellular Location |
Nucleus {ECO:0000250}.
|