KCNH1

Gene Symbol	KCNH1
Entrez Gene	3756
Alt Symbol	EAG, EAG1, Kv10.1, TMBTS, h-eag
Species	Human
Gene Type	protein-coding
Description	potassium channel, voltage gated eag related subfamily H, member 1
Other Description	EAG channel 1|ether-a-go-go potassium channel 1|ether-a-go-go, Drosophila, homolog of|hEAG1|potassium voltage-gated channel subfamily H member 1|potassium voltage-gated channel, subfamily H (eag-related), member 1|voltage-gated potassium channel subunit Kv10.1
Swissprots	O76035 Q14CL3 O95259 B1AQ26
Accessions	CCQ43886 EAW93424 EAW93425 O95259 AF078741 AAC68668 AF078742 AAC68669 AJ001366 CAA04700 AK127526 BC113709 AAI13710 BC143599 AAI43600 XM_011509514 XP_011507816 NM_002238 NP_002229 NM_172362 NP_758872
Function	Pore-forming (alpha) subunit of a voltage-gated delayed rectifier potassium channel (PubMed:22732247). Channel properties may be modulated by subunit assembly, but not by cyclic nucleotides (By similarity). Mediates IK(NI) current in myoblasts (PubMed:9738473). Involved in the regulation of cell proliferation and differentiation, in particular adipogenic and osteogenic differentiation in bone marrow-derived mesenchymal stem cells (MSCs) (PubMed:23881642). {ECO:0000250|UniProtKB:Q60603, ECO:0000269|PubMed:22732247, ECO:0000269|PubMed:23881642, ECO:0000269|PubMed:9738473}.
Subcellular Location	Cell membrane {ECO:0000269|PubMed:21559285, ECO:0000269|PubMed:22732247, ECO:0000269|PubMed:22841712}; Multi- pass membrane protein {ECO:0000269|PubMed:21559285}. Nucleus inner membrane {ECO:0000269|PubMed:21559285}; Multi-pass membrane protein {ECO:0000269|PubMed:21559285}. Early endosome membrane {ECO:0000269|PubMed:22841712}. Note=Perinuclear KCNH1 is located to NPC-free islands.
Tissue Specificity	Highly expressed in brain and in myoblasts at the onset of fusion, but not in other tissues. Detected in HeLa (cervical carcinoma), SH-SY5Y (neuroblastoma) and MCF-7 (epithelial tumor) cells, but not in normal epithelial cells.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

KCNH1 overexpression lysate - LY406729 from Acris Antibodies Category Cell Lysate Prices $480.00 Sizes 100 µg

KCNH1 overexpression lysate - LY419457 from Acris Antibodies Category Cell Lysate Prices $480.00 Sizes 100 µg

KCNH1 overexpression lysate - LY429091 from Acris Antibodies Category Cell Lysate Prices $480.00 Sizes 100 µg

KCNH1 293 Cell Lysate - 404014 from ABBIOTEC Category Cell Lysate Prices $672.00 Sizes 100 µg

KCNH1 Overexpression Lysate (Native) - NBP2-08137 from Novus Biologicals Category Cell Lysate Prices $529.00 Sizes 100 µg

KCNH1 Over-expression Lysate Product - GWB-1A57AF from Genway Biotech Category Cell Lysate Prices $756.00 Sizes 100 µg Species Human

KCNH1 Overexpression Lysate (Native) - NBP2-09780 from Novus Biologicals Category Cell Lysate Prices $529.00 Sizes 100 µg

Panoply™ Human KCNH1 Knockdown Stable Cell Line - CSC-DC007948 from Creative biogene Category Cell Line Species Human

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