Gene Symbol | NEFL |
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Entrez Gene | 4747 |
Alt Symbol | CMT1F, CMT2E, NF-L, NF68, NFL, PPP1R110 |
Species | Human |
Gene Type | protein-coding |
Description | neurofilament, light polypeptide |
Other Description | light molecular weight neurofilament protein|neurofilament light polypeptide|neurofilament protein, light chain|neurofilament subunit NF-L|neurofilament triplet L protein|neurofilament, light polypeptide 68kDa|protein phosphatase 1, regulatory subunit 110 |
Swissprots | Q16154 P07196 Q8IU72 B9ZVN2 |
Accessions | AAD14057 AAL92540 AAY79156 CAA29097 EAW63598 EAW63599 EAW63600 EAW63601 P07196 AK057731 AK075003 BAG52047 AK127430 BAG54502 AK225975 AK299095 BAG61155 AK314591 AL713644 CAD28456 AY156690 AAN74826 BC037803 BC039237 AAH39237 BC066952 AAH66952 BQ720008 DA195749 DA222123 DQ892646 ABM83572 DQ895884 ABM86810 NM_006158 NP_006149 |
Function | Neurofilaments usually contain three intermediate filament proteins: L, M, and H which are involved in the maintenance of neuronal caliber. |
Top Pathways | Amyotrophic lateral sclerosis (ALS) |
NF-L CRISPR/Cas9 KO Plasmid (h) - sc-402254 from Santa Cruz Biotechnology
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NF-L HDR Plasmid (h) - sc-402254-HDR from Santa Cruz Biotechnology
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NF-L Double Nickase Plasmid (h) - sc-402254-NIC from Santa Cruz Biotechnology
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NF-L Double Nickase Plasmid (h2) - sc-402254-NIC-2 from Santa Cruz Biotechnology
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NF-L CRISPR Activation Plasmid (h) - sc-402254-ACT from Santa Cruz Biotechnology
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NF-L CRISPR Activation Plasmid (h2) - sc-402254-ACT-2 from Santa Cruz Biotechnology
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NF-L Lentiviral Activation Particles (h) - sc-402254-LAC from Santa Cruz Biotechnology
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NF-L Lentiviral Activation Particles (h2) - sc-402254-LAC-2 from Santa Cruz Biotechnology
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NF-L siRNA (h) - sc-36048 from Santa Cruz Biotechnology
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NF-L shRNA Plasmid (h) - sc-36048-SH from Santa Cruz Biotechnology
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NF-L shRNA (h) Lentiviral Particles - sc-36048-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU122701 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN15192 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND15192 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR10556 from Sigma-Aldrich
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NEFL siRNA (Human) - CRH3152 from Cohesion Biosciences
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shRNA set against Human NEFL (NM_006158.3) - SHH351124 from Creative biogene
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NEFL shRNA Plasmid (Human) - CHH3152 from Cohesion Biosciences
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NEFL miRNA 3'UTR clone - MiUTR3H-01528 from Creative biogene
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