SOS1

Gene Symbol	SOS1
Entrez Gene	6654
Alt Symbol	GF1, GGF1, GINGF, HGF, NS4
Species	Human
Gene Type	protein-coding
Description	son of sevenless homolog 1 (Drosophila)
Other Description	SOS-1|gingival fibromatosis, hereditary, 1|guanine nucleotide exchange factor|son of sevenless homolog 1
Swissprots	Q07889 A8K2G3 B4DXG2
Accessions	AAF04460 AAM22406 AAX93186 AAY24202 CBX55730 EAX00350 EAX00351 EAX00352 EAX00353 Q07889 AB209140 BAD92377 AK290228 BAF82917 AK301960 BAG63374 AL833457 AV702692 BC140215 AAI40216 L13857 AAA35913 XM_005264515 XP_005264572 XM_011533060 XP_011531362 XM_011533061 XP_011531363 XM_011533062 XP_011531364 XM_011533063 XP_011531365 XM_011533064 XP_011531366 XM_011533065 XP_011531367 XM_011533066 XP_011531368 NM_005633 NP_005624
Function	Promotes the exchange of Ras-bound GDP by GTP. Catalytic component of a trimeric complex that participates in transduction of signals from Ras to Rac by promoting the Rac-specific guanine nucleotide exchange factor (GEF) activity (By similarity). {ECO:0000250}.
Tissue Specificity	Expressed in gingival tissues. {ECO:0000269|PubMed:11868160}.
Top Pathways	Alcoholism, Prolactin signaling pathway, PI3K-Akt signaling pathway, MicroRNAs in cancer, Estrogen signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Sos 1 CRISPR/Cas9 KO Plasmid (h) - sc-401135 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

Sos 1 HDR Plasmid (h) - sc-401135-HDR from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Sos 1 Double Nickase Plasmid (h) - sc-401135-NIC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Sos 1 Double Nickase Plasmid (h2) - sc-401135-NIC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Sos 1 CRISPR Activation Plasmid (h) - sc-401135-ACT from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

Sos 1 CRISPR Activation Plasmid (h2) - sc-401135-ACT-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

Sos 1 Lentiviral Activation Particles (h) - sc-401135-LAC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Sos 1 Lentiviral Activation Particles (h2) - sc-401135-LAC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Sos 1 siRNA (h) - sc-29486 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

Sos 1 shRNA Plasmid (h) - sc-29486-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

Sos 1 shRNA (h) Lentiviral Particles - sc-29486-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

MISSION® esiRNA - EHU017831 from Sigma-Aldrich Category siRNA Prices $140.00, $250.00 Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN20342 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND20342 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

SOS1 siRNA (Human) - CRH4534 from Cohesion Biosciences Category siRNA Prices $340.00, $510.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

SOS1 RNAi - H00006654-R01 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

SOS1 - MBS8204857 from MyBioSource Prices $365.00, $515.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

Sos 1 CRISPR/Cas9 KO Plasmid (h2) - sc-401135-KO-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

Sos 1 HDR Plasmid (h2) - sc-401135-HDR-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

shRNA set against Human Sos1 (NM_005633.3) - SHH415212 from Creative biogene Category siRNA Species Reactivities Human

shRNA set against Human SOS1(NM_005633.3) - SHL016806 from Creative biogene Category siRNA Species Reactivities Human

Human SOS1 siRNA - orb265036 from Biorbyt Category siRNA Prices $485.00, $629.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

SOS1 shRNA Plasmid (Human) - CHH4534 from Cohesion Biosciences Category siRNA Prices $500.00, $750.00 Sizes 150 µg, 300 µg Species Reactivities Human

SOS1 miRNA 3'UTR clone - MiUTR1H-09754 from Creative biogene Species Reactivities Human

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