| Gene Symbol |
SOS1
|
| Entrez Gene |
6654
|
| Alt Symbol |
GF1, GGF1, GINGF, HGF, NS4
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
son of sevenless homolog 1 (Drosophila)
|
| Other Description |
SOS-1|gingival fibromatosis, hereditary, 1|guanine nucleotide exchange factor|son of sevenless homolog 1
|
| Swissprots |
Q07889 A8K2G3 B4DXG2
|
| Accessions |
AAF04460 AAM22406 AAX93186 AAY24202 CBX55730 EAX00350 EAX00351 EAX00352 EAX00353 Q07889 AB209140 BAD92377 AK290228 BAF82917 AK301960 BAG63374 AL833457 AV702692 BC140215 AAI40216 L13857 AAA35913 XM_005264515 XP_005264572 XM_011533060 XP_011531362 XM_011533061 XP_011531363 XM_011533062 XP_011531364 XM_011533063 XP_011531365 XM_011533064 XP_011531366 XM_011533065 XP_011531367 XM_011533066 XP_011531368 NM_005633 NP_005624
|
| Function |
Promotes the exchange of Ras-bound GDP by GTP. Catalytic component of a trimeric complex that participates in transduction of signals from Ras to Rac by promoting the Rac-specific guanine nucleotide exchange factor (GEF) activity (By similarity). {ECO:0000250}.
|
| Tissue Specificity |
Expressed in gingival tissues. {ECO:0000269|PubMed:11868160}.
|
| Top Pathways |
Alcoholism, Prolactin signaling pathway, PI3K-Akt signaling pathway, MicroRNAs in cancer, Estrogen signaling pathway
|