Gene Symbol | APOC1 |
---|---|
Entrez Gene | 341 |
Alt Symbol | Apo-CI, ApoC-I |
Species | Human |
Gene Type | protein-coding |
Description | apolipoprotein C-I |
Other Description | apo-CIB|apoC-IB|apolipoprotein C-I variant I|apolipoprotein C1 |
Swissprots | Q6IB97 B2R526 P02654 |
Accessions | AAA51763 AAA88018 AAD02506 AAQ91813 ACN81312 EAW57307 EAW57308 P02654 AF308154 AAG49499 AF308155 AAG49500 AI310334 AI885116 AK225971 AK312036 BAG34973 AM392727 CAL37605 BC009698 AAH09698 BC055093 AAH55093 BT007142 AAP35806 CR456907 CAG33188 GQ129384 ACT64518 GQ129385 ACT64519 M27359 AAA51762 X00570 CAA25235 XM_005258855 XP_005258912 NM_001645 NP_001636 |
Function | Inhibitor of lipoprotein binding to the low density lipoprotein (LDL) receptor, LDL receptor-related protein, and very low density lipoprotein (VLDL) receptor. Associates with high density lipoproteins (HDL) and the triacylglycerol-rich lipoproteins in the plasma and makes up about 10% of the protein of the VLDL and 2% of that of HDL. Appears to interfere directly with fatty acid uptake and is also the major plasma inhibitor of cholesteryl ester transfer protein (CETP). Binds free fatty acids and reduces their intracellular esterification. Modulates the interaction of APOE with beta-migrating VLDL and inhibits binding of beta-VLDL to the LDL receptor-related protein. {ECO:0000269|PubMed:17339654, ECO:0000303|PubMed:25160599}. |
Subcellular Location | Secreted {ECO:0000303|PubMed:2835369}. |
Tissue Specificity | Synthesized mainly in liver and to a minor degree in intestine. Also found in the lung and spleen. {ECO:0000269|PubMed:2835369}. |
Apolipoprotein CI (APOCI) Human ELISA Kit - ab108808 from Abcam
|
||||||||||
Human Apolipoprotein C-I ELISA Kit (Sandwich ELISA) - LS-F5230 from LifeSpan Bioscience
|
||||||||||
Mouse Apolipoprotein C-I ELISA Kit (Sandwich ELISA) - LS-F5921 from LifeSpan Bioscience
|
||||||||||
Rabbit APOC1 / Apolipoprotein C I ELISA Kit - LS-F10868 from LifeSpan Bioscience
|
||||||||||
Human Apolipoprotein C-I ELISA Kit (Sandwich ELISA) - LS-F10866 from LifeSpan Bioscience
|
||||||||||
Mouse Apolipoprotein C-I ELISA Kit (Sandwich ELISA) - LS-F10867 from LifeSpan Bioscience
|
||||||||||
Human APOC1 / Apolipoprotein C-I ELISA Kit - RAB0611 from Sigma-Aldrich
|
||||||||||
Human ApoC1 ELISA kit - orb158913 from Biorbyt
|
||||||||||
Human Apolipoprotein C1 ELISA Kit - abx150712 from Abbexa
|
||||||||||
Apolipoprotein C1, ApoC1, Human, ELISA Kit - E-EL-H0465 from ARP American Research Products
|
||||||||||
Apolipoprotein C-I (APOC1), Human, ELISA Kit - CSB-E13807h from ARP American Research Products
|
||||||||||
Apolipoprotein C-I, APOC1, Human, ELISA Kit - E0252h from ARP American Research Products
|
||||||||||
Apolipoprotein C1 (APOC1), Human, ELISA Kit - SEA252Hu from ARP American Research Products
|
||||||||||
Apolipoprotein C1, Human, ELISA Kit - E01A0514 from ARP American Research Products
|
||||||||||
Apolipoprotein C1, APO-C1, Mouse, ELISA Kit - E-EL-M0133 from ARP American Research Products
|
||||||||||
Apolipoprotein C1, ApoC1, Rabbit, ELISA Kit - E-EL-RB1637 from ARP American Research Products
|
||||||||||
Apolipoprotein C1, ApoC1, Chicken, ELISA Kit - E-EL-Ch1478 from ARP American Research Products
|
||||||||||
ApoC1 (Apolipoprotein C1), Pig, ELISA Kit - E-EL-P0420 from ARP American Research Products
|
||||||||||
Apolipoprotein C1, ApoC1, Sheep, ELISA Kit - E-EL-S0356 from ARP American Research Products
|
||||||||||
Apolipoprotein C1, ApoC1, Guinea Pig, ELISA Kit - E-EL-GP0235 from ARP American Research Products
|
||||||||||
Apolipoprotein C1, ApoC1, Monkey, ELISA Kit - E-EL-MK1767 from ARP American Research Products
|
||||||||||
APOC1 (Human) ELISA kit - KA0463 from Acris Antibodies
|
||||||||||
Human ApoC1 ELISA - ELH-ApoC1 from RayBiotech
|
||||||||||
Human APOC1 ELISA Kit - HA0521 from NeoScientific
|
||||||||||
Anserine APOC1 ELISA Kit - AA0521 from NeoScientific
|