SPTLC2

Gene Symbol	SPTLC2
Entrez Gene	9517
Alt Symbol	HSN1C, LCB2, LCB2A, NSAN1C, SPT2, hLCB2a
Species	Human
Gene Type	protein-coding
Description	serine palmitoyltransferase, long chain base subunit 2
Other Description	LCB 2|SPT 2|long chain base biosynthesis protein 2a|serine palmitoyltransferase 2|serine palmitoyltransferase, subunit II|serine-palmitoyl-CoA transferase 2
Swissprots	Q16685 O15270
Accessions	AAD09621 EAW81297 EAW81298 EAW81299 O15270 AB011098 BAA25452 BC005123 AAH05123 BG024616 BM992457 BQ338973 DQ893297 ABM84223 DQ896786 ABM87785 U15555 AAC50871 W24363 Y08686 CAA69942 XM_011537384 XP_011535686 NM_004863 NP_004854
Function	Serine palmitoyltransferase (SPT). The heterodimer formed with LCB1/SPTLC1 constitutes the catalytic core. The composition of the serine palmitoyltransferase (SPT) complex determines the substrate preference. The SPTLC1-SPTLC2-SPTSSA complex shows a strong preference for C16-CoA substrate, while the SPTLC1-SPTLC2-SPTSSB complex displays a preference for C18-CoA substrate. {ECO:0000269|PubMed:19416851, ECO:0000269|PubMed:20920666}.
Subcellular Location	Endoplasmic reticulum membrane {ECO:0000250}; Single-pass membrane protein {ECO:0000250}.
Tissue Specificity	Widely expressed. {ECO:0000269|PubMed:17023427}.
Top Pathways	Sphingolipid signaling pathway, Sphingolipid metabolism

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human Serine Palmitoyltransferase full length protein - ab152996 from Abcam Category Protein Source Wheat germ Species Human

Human Serine Palmitoyltransferase protein fragment - ab152997 from Abcam Category Protein Source Wheat germ Species Human

SPTLC2 / LCB2 Antibody Blocking Peptide - LS-E17589 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

SPTLC2 / LCB2 Antibody Blocking Peptide - LS-E6993 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

SPTLC2 / LCB2 Antibody Blocking Peptide - LS-E31116 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

Recombinant Human Serine Palmitoyltransferase 2 Protein - H00009517-P01 from Novus Biologicals Category Protein Prices $319.00 Sizes 2 µg Source Wheat Germ Species Human

Recombinant Human Serine Palmitoyltransferase 2 Protein - H00009517-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Serine Palmitoyltransferase 2 Blocking Peptide - NBP1-76573PEP from Novus Biologicals Category Peptide Prices $129.00 Sizes 50 µg Species Human

Serine Palmitoyltransferase 2 Peptide - P1146 from Novus Biologicals Category Peptide Species Human

Serine-Palmitoyltransferase-SPTLC2-Antibody-C-term-Blocking-peptide - BP2533b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Human SPTLC2 protein - orb246442 from Biorbyt Category Protein Prices $340.00, $629.00, $1,003.00, $1,556.00 Sizes 50 μg, 200 μg, 500 μg, 1 mg Species Human

SPTLC2 Blocking Peptide - 33R-9690 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

SPTLC2 - H00009517-P01 from Acris Antibodies Category Protein Prices $340.00 Sizes 2 µg Species Human

SPTLC2 - H00009517-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

SPTLC2 - H00009517-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

SPT2 Peptide - 6305P from ProSci Category Peptide Species Human

SPTLC2 fusion protein - ag7774 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Serine Palmitoyltransferase, Long Chain Base Subunit 2 (SPTLC2) - RPH137Mu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Mouse

Recombinant Serine Palmitoyltransferase, Long Chain Base Subunit 2 (SPTLC2) - RPH137Mu02 from Uscn Life Science Inc. Category Protein Source E.coli Species Mouse

Recombinant human Serine palmitoyltransferase 2 - CSB-YP022640HU CSB-BP022640HU CSB-MP022640HU from Cusabio Category Protein Source Yeast or Baculovirus or Mammalian cell Species Human

Recombinant human Serine palmitoyltransferase 2 - CSB-EP022640HU from Cusabio Category Protein Source E.coli Species Human

Serine Palmitoyltransferase 2 Protein - NBP1-92379PEP from Novus Biologicals Category Protein Prices $209.00 Sizes 100 µl Species Human

Serine-Palmitoyltransferase-SPTLC2-Antibody-N-term-Blocking-peptide - BP2533a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

SPTLC2-Blocking-Peptide-Center - BP20262c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

SPTLC2 Peptide, Human - M34GP15123H from Creative Peptides Category Peptide Source Synthetic. Species Human

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