SPTLC2

Gene Symbol	SPTLC2
Entrez Gene	9517
Alt Symbol	HSN1C, LCB2, LCB2A, NSAN1C, SPT2, hLCB2a
Species	Human
Gene Type	protein-coding
Description	serine palmitoyltransferase, long chain base subunit 2
Other Description	LCB 2|SPT 2|long chain base biosynthesis protein 2a|serine palmitoyltransferase 2|serine palmitoyltransferase, subunit II|serine-palmitoyl-CoA transferase 2
Swissprots	Q16685 O15270
Accessions	AAD09621 EAW81297 EAW81298 EAW81299 O15270 AB011098 BAA25452 BC005123 AAH05123 BG024616 BM992457 BQ338973 DQ893297 ABM84223 DQ896786 ABM87785 U15555 AAC50871 W24363 Y08686 CAA69942 XM_011537384 XP_011535686 NM_004863 NP_004854
Function	Serine palmitoyltransferase (SPT). The heterodimer formed with LCB1/SPTLC1 constitutes the catalytic core. The composition of the serine palmitoyltransferase (SPT) complex determines the substrate preference. The SPTLC1-SPTLC2-SPTSSA complex shows a strong preference for C16-CoA substrate, while the SPTLC1-SPTLC2-SPTSSB complex displays a preference for C18-CoA substrate. {ECO:0000269|PubMed:19416851, ECO:0000269|PubMed:20920666}.
Subcellular Location	Endoplasmic reticulum membrane {ECO:0000250}; Single-pass membrane protein {ECO:0000250}.
Tissue Specificity	Widely expressed. {ECO:0000269|PubMed:17023427}.
Top Pathways	Sphingolipid signaling pathway, Sphingolipid metabolism

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

SPTLC2 (G-4) - sc-398704 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Mouse Clonality Monoclonal

SPTLC2 (C-20) - sc-27500 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

SPTLC2 (G-19) - sc-27499 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

SPTLC2 (H-148) - sc-366002 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Rabbit Clonality Polyclonal

Anti-Serine Palmitoyltransferase antibody - ab85633 from Abcam Prices $376.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-Serine Palmitoyltransferase antibody - ab23696 from Abcam Prices $382.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

Anti-Serine Palmitoyltransferase antibody - C-terminal - ab194575 from Abcam Prices $376.00 Sizes 50 µl Host Mouse Clonality Polyclonal

Anti-Serine Palmitoyltransferase antibody - C-terminal - ab71631 from Abcam Prices $376.00 Sizes 400 µl Host Rabbit Clonality Polyclonal

Anti-SPTLC2 / LCB2 Antibody (aa372-401, AP) - LS-C217718 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-SPTLC2 / LCB2 Antibody (aa372-401, APC) - LS-C217719 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-SPTLC2 / LCB2 Antibody (aa372-401, Biotin) - LS-C217720 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-SPTLC2 / LCB2 Antibody (aa372-401, FITC) - LS-C217721 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-SPTLC2 / LCB2 Antibody (aa372-401, Azide-free, HRP) - LS-C217722 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-SPTLC2 / LCB2 Antibody (aa372-401, PE) - LS-C217723 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-SPTLC2 / LCB2 Antibody (C-Terminus, AP) - LS-C220763 from LifeSpan Bioscience Prices $515.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-SPTLC2 / LCB2 Antibody (C-Terminus, APC) - LS-C220764 from LifeSpan Bioscience Prices $515.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-SPTLC2 / LCB2 Antibody (C-Terminus, Biotin) - LS-C220765 from LifeSpan Bioscience Prices $515.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-SPTLC2 / LCB2 Antibody (C-Terminus, FITC) - LS-C220766 from LifeSpan Bioscience Prices $515.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-SPTLC2 / LCB2 Antibody (C-Terminus, Azide-free, HRP) - LS-C220767 from LifeSpan Bioscience Prices $515.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-SPTLC2 / LCB2 Antibody (C-Terminus, PE) - LS-C220768 from LifeSpan Bioscience Prices $515.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-SPTLC2 / LCB2 Antibody (aa372-401) - LS-C325363 from LifeSpan Bioscience Prices $345.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-SPTLC2 / LCB2 Antibody (aa72-121) - LS-C102311 from LifeSpan Bioscience Prices $365.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

Anti-SPTLC2 / LCB2 Antibody (C-Terminus) - LS-C328742 from LifeSpan Bioscience Prices $345.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-SPTLC2 / LCB2 Antibody (aa372-401) - LS-C156125 from LifeSpan Bioscience Prices $295.00 Sizes 400 µl Host Rabbit Clonality Polyclonal

Anti-SPTLC2 / LCB2 Antibody (aa531-562) - LS-C98505 from LifeSpan Bioscience Prices $295.00 Sizes 400 µl Host Rabbit Clonality Polyclonal

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