ACVR1

Gene Symbol	ACVR1
Entrez Gene	90
Alt Symbol	ACTRI, ACVR1A, ACVRLK2, ALK2, FOP, SKR1, TSRI
Species	Human
Gene Type	protein-coding
Description	activin A receptor, type I
Other Description	TGF-B superfamily receptor type I|activin A receptor, type II-like kinase 2|activin receptor type I|activin receptor type-1|activin receptor-like kinase 2|hydroxyalkyl-protein kinase|serine/threonine-protein kinase receptor R1
Swissprots	Q04771
Accessions	AAY15094 AAY24272 ADL14509 AJF45349 CAA02405 CAZ91465 CBX47654 EAX11438 EAX11439 EAX11440 EAX11441 EAX11442 EAX11443 Q04771 AK297765 BAG60113 AK313630 BC033867 AAH33867 BC036748 DA796090 L02911 AAA36614 Z22534 CAA80256 XM_005246939 XP_005246996 XM_005246940 XP_005246997 XM_006712825 XP_006712888 XM_011512106 XP_011510408 XM_011512107 XP_011510409 XM_011512108 XP_011510410 NM_001105 NP_001096 NM_001111067 NP_001104537
Function	On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for activin. May be involved for left-right pattern formation during embryogenesis (By similarity). {ECO:0000250}.
Subcellular Location	Membrane; Single-pass type I membrane protein.
Tissue Specificity	Expressed in normal parenchymal cells, endothelial cells, fibroblasts and tumor-derived epithelial cells.
Top Pathways	Cytokine-cytokine receptor interaction, TGF-beta signaling pathway, Signaling pathways regulating pluripotency of stem cells

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human-ACVR1-cDNA-Clone - DC06679 from Abgent, a WuXi AppTec company Prices $688.50 Sizes 10 µg Species Human Accession NM_001105

Human Activin RIA/ALK-2 (NP_001096) VersaClone cDNA - RDC1201 from R&D Systems Prices $199.00 Sizes 10 µg Species Human

ACVR1 cDNA (ANA10191) - ANA10191 from Aviva Systems Biology Prices $189.00 Sizes 1 µg Accession BC033867

ACVR1 cDNA (ANA10192) - ANA10192 from Aviva Systems Biology Prices $189.00 Sizes 1 µg Accession BC033867

Human ACVR1 ORF Clone(NM_001105.4) - CDCL153079 from Creative Biomart Species Human Accession NM_001105.4

Human ACVR1 ORF Clone(NM_001105.4) - CDCL153080 from Creative Biomart Species Human Accession NM_001105.4

Human ACVR1 ORF Clone(NM_001111067.2) - CDCR347828 from Creative Biomart Species Human Accession NM_001111067.2

Human ACVR1 ORF Clone(NM_001111067.2) - CDCR347829 from Creative Biomart Species Human Accession NM_001111067.2

Human ACVR1 ORF clone(NM_001111067.2) - CDCL182563 from Creative Biomart Species Human Accession NM_001111067.2

Human ALK-2/ACVR1 Gene ORF cDNA clone in cloning vector - HG14875-G from Sino Biological Species Human

Human ALK-2/ACVR1 transcript variant 2 Gene ORF cDNA clone in cloning vector - HG10227-M from Sino Biological Species Human

Human ALK-2/ACVR1 Gene ORF cDNA clone expression plasmid, C-His tag - HG14875-CH from Sino Biological Species Human

Human ALK-2/ACVR1 transcript variant 2 Gene ORF cDNA clone expression plasmid - HG10227-UT from Sino Biological Species Human

Human ALK-2/ACVR1 transcript variant 2 Gene ORF cDNA clone expression plasmid, C-HA tag - HG10227-CY from Sino Biological Species Human

Human ALK-2/ACVR1 transcript variant 2 Gene ORF cDNA clone expression plasmid, N-Flag tag - HG10227-NF from Sino Biological Species Human

Human ALK-2/ACVR1 Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG14875-ACR from Sino Biological Species Human

Human ALK-2/ACVR1 transcript variant 2 Gene ORF cDNA clone expression plasmid, C-His tag - HG10227-CH from Sino Biological Species Human

Human ALK-2/ACVR1 transcript variant 2 Gene ORF cDNA clone expression plasmid, C-Flag tag - HG10227-CF from Sino Biological Species Human

Human ALK-2/ACVR1 transcript variant 2 Gene ORF cDNA clone expression plasmid, N-Myc tag - HG10227-NM from Sino Biological Species Human

Human ALK-2/ACVR1 Gene ORF cDNA clone expression plasmid, C-HA tag - HG14875-CY from Sino Biological Species Human

Human ALK-2/ACVR1 transcript variant 2 Gene ORF cDNA clone expression plasmid, N-HA tag - HG10227-NY from Sino Biological Species Human

Human ALK-2/ACVR1 transcript variant 2 Gene ORF cDNA clone expression plasmid, C-Flag tag - HG10227-M-F from Sino Biological Species Human

Human ALK-2/ACVR1 transcript variant 2 Gene ORF cDNA clone expression plasmid, C-Myc tag - HG10227-CM from Sino Biological Species Human

Human ALK-2/ACVR1 Gene ORF cDNA clone expression plasmid - HG14875-UT from Sino Biological Species Human

Human ALK-2/ACVR1 Gene ORF cDNA clone expression plasmid, N-Flag tag - HG14875-NF from Sino Biological Species Human

Search more