| Gene Symbol |
KCNK1
|
| Entrez Gene |
3775
|
| Alt Symbol |
DPK, HOHO, K2P1, K2p1.1, KCNO1, TWIK-1, TWIK1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
potassium channel, two pore domain subfamily K, member 1
|
| Other Description |
inward rectifying potassium channel protein TWIK-1|potassium channel KCNO1|potassium channel subfamily K member 1|potassium inwardly-rectifying channel, subfamily K, member 1|tandem of P domains in a weak inward rectifying K+ channel 1
|
| Swissprots |
Q5T5E8 O00180 Q13307
|
| Accessions |
EAW69989 EAW69990 O00180 AK090902 AK314016 BAG36727 BC018051 AAH18051 BQ022191 DQ892383 ABM83309 DQ895595 ABM86521 U33632 AAB01688 U76996 AAB97878 U90065 AAB51147 XM_011544184 XP_011542486 NM_002245 NP_002236
|
| Function |
Weakly inward rectifying potassium channel that contributes to the regulation of the resting membrane potential. {ECO:0000269|PubMed:22282804, ECO:0000269|PubMed:8605869}.
|
| Subcellular Location |
Cell membrane {ECO:0000269|PubMed:8605869}; Multi-pass membrane protein {ECO:0000269|PubMed:22282804}.
|
| Tissue Specificity |
Widely expressed with high levels in heart and brain and lower levels in placenta, lung, liver and kidney (PubMed:8605869). {ECO:0000269|PubMed:8605869}.
|
![Western Blot: KCNK1 Overexpression Lysate (Adult Normal) [NBL1-12176] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for KCNK1.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/5609_KCNK1%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-12176-img0002.jpg)