Gene Symbol | SERPINC1 |
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Entrez Gene | 540261 |
Alt Symbol | AT3 |
Species | Bovine |
Gene Type | protein-coding |
Description | serpin peptidase inhibitor, clade C (antithrombin), member 1 |
Other Description | ATIII|antithrombin III|antithrombin-III|serine (or cysteine) proteinase inhibitor, clade C (antithrombin), member 1|serpin C1 |
Swissprots | Q3SZQ7 P41361 |
Accessions | DAA21124 P41361 BC102747 AAI02748 NM_001034698 NP_001029870 |
Function | Most important serine protease inhibitor in plasma that regulates the blood coagulation cascade. AT-III inhibits thrombin, matriptase-3/TMPRSS7, as well as factors IXa, Xa and XIa. Its inhibitory activity is greatly enhanced in the presence of heparin (By similarity). {ECO:0000250}. |
Subcellular Location | Secreted, extracellular space {ECO:0000250}. |
Tissue Specificity | Plasma. |
Top Pathways | Complement and coagulation cascades |
Bovine Antithrombin III (AT III) - PA60114 from AssayPro
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Recombinant Bovine Antithrombin-III(SERPINC1) - CSB-YP021079BO CSB-EP021079BO CSB-BP021079BO CSB-MP021079BO from Cusabio
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Antithrombin-III (SERPINC1) , Recombinant Protein - MBS964649 from MyBioSource
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SERPINC1 Recombinant Protein (OPCD01515) - OPCD01515 from Aviva Systems Biology
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