Gene Symbol | SERPINC1 |
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Entrez Gene | 540261 |
Alt Symbol | AT3 |
Species | Bovine |
Gene Type | protein-coding |
Description | serpin peptidase inhibitor, clade C (antithrombin), member 1 |
Other Description | ATIII|antithrombin III|antithrombin-III|serine (or cysteine) proteinase inhibitor, clade C (antithrombin), member 1|serpin C1 |
Swissprots | Q3SZQ7 P41361 |
Accessions | DAA21124 P41361 BC102747 AAI02748 NM_001034698 NP_001029870 |
Function | Most important serine protease inhibitor in plasma that regulates the blood coagulation cascade. AT-III inhibits thrombin, matriptase-3/TMPRSS7, as well as factors IXa, Xa and XIa. Its inhibitory activity is greatly enhanced in the presence of heparin (By similarity). {ECO:0000250}. |
Subcellular Location | Secreted, extracellular space {ECO:0000250}. |
Tissue Specificity | Plasma. |
Top Pathways | Complement and coagulation cascades |
Anti-Antithrombin III antibody - ab180614 from Abcam
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Anti-Antithrombin III antibody - ab182962 from Abcam
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Anti-Antithrombin III antibody - ab105849 from Abcam
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Anti-Antithrombin III antibody (Biotin) - ab105850 from Abcam
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Anti-Antithrombin III antibody - N-terminal - ab181689 from Abcam
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Anti-antithrombin III polyclonal antibody - DPABH-00080 from Creative Diagnostics
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Rabbit Anti-Human SERPINC1 Polyclonal antibody - DPABH-00081 from Creative Diagnostics
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Bovine Antithrombin III (AT III) Antibody - 22111-05011 from AssayPro
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Bovine Antithrombin III (AT III) Antibody (Biotin Conjugate) - 22111-05021 from AssayPro
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Antithrombin III - ASP-230 from Nordic BioSite
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Antithrombin III - ASP-229 from Nordic BioSite
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Antithrombin, Polyclonal Antibody - MBS2028564 from MyBioSource
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