| Gene Symbol |
Gpaa1
|
| Entrez Gene |
14731
|
| Alt Symbol |
C80044, mGAA1
|
| Species |
Mouse
|
| Gene Type |
protein-coding
|
| Description |
GPI anchor attachment protein 1
|
| Other Description |
GAA1 protein homolog|glycosylphosphatidylinositol anchor attachment 1 protein
|
| Swissprots |
Q3TNU9 Q9WTK3 Q9R1U8
|
| Accessions |
BAA82586 BAA82591 BAB03275 EDL29547 EDL29548 Q9WTK3 AB002136 BAA82589 AB006970 BAB03274 AK077518 BAC36840 AK164219 BAE37686 AK164978 BAE37988 AK168057 AK177221 AK188140 AK192435 AK200986 AK212219 BC006697 AAH06697 XM_011245457 XP_011243759 NM_010331 NP_034461
|
| Function |
Essential for GPI-anchoring of precursor proteins but not for GPI synthesis. Acts before or during formation of the carbonyl intermediate. {ECO:0000269|PubMed:10793132, ECO:0000269|PubMed:10898732}.
|
| Subcellular Location |
Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
|
| Tissue Specificity |
Ubiquitously expressed in fetal and adult tissues. Expressed at higher levels in fetal tissues than adult tissues. In embryos abundant in the choroid plexus, skeletal muscle,. {ECO:0000269|PubMed:10898732}.
|
| Top Pathways |
Glycosylphosphatidylinositol(GPI)-anchor biosynthesis
|