| Gene Symbol | Gpaa1 |
|---|---|
| Entrez Gene | 14731 |
| Alt Symbol | C80044, mGAA1 |
| Species | Mouse |
| Gene Type | protein-coding |
| Description | GPI anchor attachment protein 1 |
| Other Description | GAA1 protein homolog|glycosylphosphatidylinositol anchor attachment 1 protein |
| Swissprots | Q3TNU9 Q9WTK3 Q9R1U8 |
| Accessions | BAA82586 BAA82591 BAB03275 EDL29547 EDL29548 Q9WTK3 AB002136 BAA82589 AB006970 BAB03274 AK077518 BAC36840 AK164219 BAE37686 AK164978 BAE37988 AK168057 AK177221 AK188140 AK192435 AK200986 AK212219 BC006697 AAH06697 XM_011245457 XP_011243759 NM_010331 NP_034461 |
| Function | Essential for GPI-anchoring of precursor proteins but not for GPI synthesis. Acts before or during formation of the carbonyl intermediate. {ECO:0000269|PubMed:10793132, ECO:0000269|PubMed:10898732}. |
| Subcellular Location | Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. |
| Tissue Specificity | Ubiquitously expressed in fetal and adult tissues. Expressed at higher levels in fetal tissues than adult tissues. In embryos abundant in the choroid plexus, skeletal muscle,. {ECO:0000269|PubMed:10898732}. |
| Top Pathways | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis |