CHRNA1

Gene Symbol CHRNA1
Entrez Gene 1134
Alt Symbol ACHRA, ACHRD, CHRNA, CMS2A, FCCMS, SCCMS
Species Human
Gene Type protein-coding
Description cholinergic receptor, nicotinic, alpha 1 (muscle)
Other Description acetylcholine receptor subunit alpha|acetylcholine receptor, nicotinic, alpha 1 (muscle)|cholinergic receptor, nicotinic, alpha polypeptide 1 (muscle)|muscle nicotinic acetylcholine receptor|nicotinic acetylcholine receptor alpha subunit|nicotinic cholinergic receptor alpha 1
Swissprots D3DPE8 B4DRV6 P02708
Accessions AAY14687 CAA26344 CAA34960 CAA49705 EAX11124 EAX11125 EAX11126 EAX11127 EAX11128 P02708 AK291338 BAF84027 AK299445 BAG61418 AK315312 BAG37716 BC006314 BC043196 BG828551 CD013889 DQ323657 ABD27888 DQ323658 ABD27889 S77094 AAD14247 Y00762 CAA68731 NM_000079 NP_000070 NM_001039523 NP_001034612
Function After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.
Subcellular Location Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
Tissue Specificity Isoform 1 is only expressed in skeletal muscle. Isoform 2 is constitutively expressed in skeletal muscle, brain, heart, kidney, liver, lung and thymus.
Top Pathways Neuroactive ligand-receptor interaction

Human Nicotinic Acetylcholine Receptor alpha 1 protein fragment - ab114482 from Abcam

Category Protein
Source Wheat germ
Species Human
12.5% SDS-PAGE showing ab114482 at approximately 35.09kDa stained with Coomassie Blue.

CHRNA1 Antibody Blocking Peptide - LS-E10717 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

Recombinant Human Nicotinic Acetylcholine R alpha 1/CHRNA1 Protein - H00001134-Q01 from Novus Biologicals

Category Protein
Prices $369.00, $529.00
Sizes 10 µg, 25 µg
Source Wheat Germ
Species Human

Nicotinic Acetylcholine R alpha 1/CHRNA1 Peptide - NBP1-07122PEP from Novus Biologicals

Category Peptide
Prices $279.00
Sizes 50 µg

CHRNA1-Antibody-C-term-Blocking-peptide - BP13550b from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

Recombinant human Acetylcholine receptor subunit alpha (OPCA00051) - OPCA00051 from Aviva Systems Biology

Category Protein
Prices $220.00
Sizes 50 µg
Species Human

Human CHRNA1 protein - orb244109 from Biorbyt

Category Protein
Prices $340.00, $629.00, $1,003.00, $1,556.00
Sizes 50 μg, 200 μg, 500 μg, 1 mg
Species Human

E.coli CHRNA1 protein - orb244112 from Biorbyt

Category Protein
Prices $340.00, $629.00, $1,003.00, $1,556.00
Sizes 50 μg, 200 μg, 500 μg, 1 mg
Species Escherichia coli

CHRNA1 Blocking Peptide - 33R-8867 from Fitzgerald

Category Peptide
Prices $130.00
Sizes 100 µg

CHRNA1 Blocking Peptide - 33R-1210 from Fitzgerald

Category Peptide
Prices $130.00
Sizes 100 µg

CHRNA1 Blocking Peptide - 33R-9265 from Fitzgerald

Category Peptide
Prices $130.00
Sizes 100 µg

CHRNA1 Blocking Peptide - abx062066 from Abbexa

Category Peptide
Species Human, Mouse, Rat, Bovine, Dog

Acetylcholine receptor alpha subunit - H00001134-Q01-10 from Acris Antibodies

Category Protein
Prices $380.00
Sizes 10 µg
Species Human

Acetylcholine receptor alpha subunit - H00001134-Q01-25 from Acris Antibodies

Category Protein
Prices $500.00
Sizes 25 µg
Species Human

CHRNA1 fusion protein - ag0933 from Proteintech Group

Category Protein
Source E. coli-derived, PGEX-4T
Species Human

CHRNA1 fusion protein - Ag4375 from Proteintech Group

Category Protein
Prices $199.00
Sizes 50 μg
Source E. coli -derived, PET28a
Species Human

Recombinant Human CHRNA1 - CHRNA1-30388TH from Creative Biomart

Category Protein
Source Wheat germ

Recombinant Cholinergic Receptor, Nicotinic, Alpha 1 (CHRNa1) - RPA981Hu01 from Uscn Life Science Inc.

Category Protein
Source E.coli
Species Human

Recombinant Cholinergic Receptor, Nicotinic, Alpha 1 (CHRNa1) - RPA981Ra01 from Uscn Life Science Inc.

Category Protein
Source E.coli
Species Rat

CHRNA1 Blocking Peptide - CBP3172 from Cohesion Biosciences

Category Peptide
Prices $100.00, $300.00
Sizes 1 mg, 5 mg
Species Human, Mouse, Rat, Bovine, Dog

AChRα1 (E217) Peptide - BS2850P from Bioworld Technology

Category Peptide
Prices $158.00
Sizes 100 µl

Acetylcholine receptor protein, alpha subunit... - pep0264 from Covalab

Category Protein
Species Human, Mouse, Rat

Recombinant Cholinergic Receptor, Nicotinic, Alpha 1 (CHRNa1) - RPA981Hu01 from Cloud-clone

Category Protein
Source E.coli
Species Human
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