HES1

Gene Symbol	HES1
Entrez Gene	3280
Alt Symbol	HES-1, HHL, HRY, bHLHb39
Species	Human
Gene Type	protein-coding
Description	hes family bHLH transcription factor 1
Other Description	class B basic helix-loop-helix protein 39|hairy homolog|hairy-like protein|transcription factor HES-1
Swissprots	Q14469 Q6FHB2
Accessions	AAA65220 EAW78058 Q14469 AF264785 AAF73060 AI370424 AK000415 BAA91149 AK300482 BAG62198 BC005178 AAH05178 BC039152 AAH39152 BC156516 AAI56517 BC172546 AAI72546 CR541843 CAG46641 DQ891328 ABM82254 DQ893354 ABM84280 DQ896673 ABM87672 DW424342 NM_005524 NP_005515
Function	Transcriptional repressor of genes that require a bHLH protein for their transcription. May act as a negative regulator of myogenesis by inhibiting the functions of MYOD1 and ASH1. Binds DNA on N-box motifs: 5'-CACNAG-3' with high affinity and on E-box motifs: 5'-CANNTG-3' with low affinity (By similarity). May play a role in a functional FA core complex response to DNA cross-link damage, being required for the stability and nuclear localization of FA core complex proteins, as well as for FANCD2 monoubiquitination in response to DNA damage. {ECO:0000250, ECO:0000269|PubMed:18550849}.
Subcellular Location	Nucleus.
Top Pathways	Notch signaling pathway, Maturity onset diabetes of the young, Fanconi anemia pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Transcription factor HES-1 (HES1), Human, ELISA Kit - CSB-EL010307HU from ARP American Research Products Category ELISA Kit Prices $495.00, $695.00, $696.00, $699.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t

hairy and enhancer of split 1, (Drosophila) , ELISA Kit - MBS910338 from MyBioSource Category ELISA Kit Prices $250.00, $495.00, $710.00, $2,705.00, $5,145.00 Sizes 24 -strip-wells (Limit 1), 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity The minimum detectable dose of human HES1 is typically less than 7 pg/ml. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined the mean O.D value of 20 replicates of the zero standard added by their three standard deviations. Range 28 pg/ml -1800 pg/ml.

Transcription factor HES 1 (HES1), ELISA Kit - MBS7203329 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Transcription factor HES-1 (HES1), ELISA Kit - MBS7246877 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Transcription factor HES-1 (HES1), ELISA Kit - MBS7245096 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Transcription factor HES-1 (HES1), ELISA Kit - MBS7202126 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Transcription factor HES-1 (HES1), ELISA Kit - MBS7229266 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 1.0 pg/mL.

Transcription factor HES-1 (HES1), ELISA Kit - MBS7240296 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Transcription factor HES-1 (HES1), ELISA Kit - MBS7228830 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Transcription factor HES-1 (HES1), ELISA Kit - MBS7219630 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 1.0 pg/mL

Transcription factor HES-1 (HES1), ELISA Kit - MBS7215033 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Transcription factor HES-1 (HES1), ELISA Kit - MBS7211473 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Transcription factor HES-1 (HES1), ELISA Kit - MBS7213526 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Human Transcription factor HES-1(HES1) ELISA kit - CSB-EL010307HU from Cusabio Category ELISA Kit Sensitivity 7 pg/ml Range 28 pg/ml-1800 pg/ml

Chicken HES1 / HES-1 ELISA Kit (Custom ELISA) - LS-F17804 from LifeSpan Bioscience Category ELISA Kit Prices $700.00 Sizes 1 plate Sensitivity To be determined Range 78-5000 pg/ml

Human HES1 / HES-1 ELISA Kit (Custom ELISA) - LS-F17806 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity To be determined Range 78-5000 pg/ml

Mouse HES1 / HES-1 ELISA Kit (Sandwich ELISA) - LS-F17807 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity 78 pg/ml Range 78-5000 pg/ml

Rat HES1 / HES-1 ELISA Kit (Custom ELISA) - LS-F17805 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity To be determined Range 78-5000 pg/ml

Bovine HES1 / HES-1 ELISA Kit (Custom ELISA) - LS-F17808 from LifeSpan Bioscience Category ELISA Kit Prices $700.00 Sizes 1 plate Sensitivity To be determined Range 78-5000 pg/ml

Human HES1(Transcription factor HES-1) ELISA Kit - E-EL-H5483 from Iwai North America Inc. Category ELISA Kit Prices $580.00 Sizes 1 kit Sensitivity 46.88 pg/mL Range 78.13~5000 pg/mL

Human Transcription factor HES-1 ELISA Kit - abx252625 from Abbexa Category ELISA Kit Sensitivity 46.875 pg/ml Range 78.125 pg/ml - 5000 pg/ml

Human Transcription factor HES-1 (HES1) ELISA Kit - EKC35828 from Biomatik Category ELISA Kit Prices $705.00, $2,820.00, $5,288.00 Sizes 96 t, 5x96t, 10x96t Sensitivity 7 pg/ml Range 28 pg/ml-1800 pg/ml

HES1 ELISA Kit (Human) (OKEH05431) - OKEH05431 from Aviva Systems Biology Category ELISA Kit Prices $500.00 Sizes 96 wells Sensitivity 39 pg/mL Range 78-5,000 pg/mL

Transcription factor HES-1, ELISA Kit - MBS2886983 from MyBioSource Category ELISA Kit Prices $430.00, $570.00, $2,515.00, $4,520.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Transcription factor HES-1, ELISA Kit - MBS763248 from MyBioSource Category ELISA Kit Prices $295.00, $390.00, $1,615.00, $3,015.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 46.875pg/ml Range 78.125-5000pg/ml

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