Gene Symbol | STARD8 |
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Entrez Gene | 9754 |
Alt Symbol | ARHGAP38, DLC3, STARTGAP3 |
Species | Human |
Gene Type | protein-coding |
Description | StAR-related lipid transfer (START) domain containing 8 |
Other Description | START domain containing 8|deleted in liver cancer 3 protein|stAR-related lipid transfer protein 8 |
Swissprots | D3DVT9 A8K6T2 Q5JST0 Q68DG7 Q92502 |
Accessions | EAX05374 EAX05375 Q92502 AK291747 BAF84436 BC035587 AAH35587 BQ019015 CR749411 CAH18253 D80011 BAA11506 DQ890917 ABM81843 XM_005262314 XP_005262371 XM_005262315 XP_005262372 XM_011531069 XP_011529371 XM_011531070 XP_011529372 NM_001142503 NP_001135975 NM_001142504 NP_001135976 NM_014725 NP_055540 |
Function | Accelerates GTPase activity of RHOA and CDC42, but not RAC1. Stimulates the hydrolysis of phosphatidylinositol 4,5- bisphosphate by PLCD1. {ECO:0000269|PubMed:17976533}. |
Subcellular Location | Cell junction, focal adhesion {ECO:0000269|PubMed:17976533}. |
Tissue Specificity | Widely expressed with highest levels in kidney, lung and placenta. {ECO:0000269|PubMed:17297465}. |
StARD8 CRISPR/Cas9 KO Plasmid (h) - sc-406594 from Santa Cruz Biotechnology
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StARD8 HDR Plasmid (h) - sc-406594-HDR from Santa Cruz Biotechnology
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StARD8 Double Nickase Plasmid (h) - sc-406594-NIC from Santa Cruz Biotechnology
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StARD8 Double Nickase Plasmid (h2) - sc-406594-NIC-2 from Santa Cruz Biotechnology
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StARD8 CRISPR Activation Plasmid (h) - sc-406594-ACT from Santa Cruz Biotechnology
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StARD8 CRISPR Activation Plasmid (h2) - sc-406594-ACT-2 from Santa Cruz Biotechnology
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StARD8 Lentiviral Activation Particles (h) - sc-406594-LAC from Santa Cruz Biotechnology
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StARD8 Lentiviral Activation Particles (h2) - sc-406594-LAC-2 from Santa Cruz Biotechnology
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StARD8 siRNA (h) - sc-63080 from Santa Cruz Biotechnology
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StARD8 shRNA Plasmid (h) - sc-63080-SH from Santa Cruz Biotechnology
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StARD8 shRNA (h) Lentiviral Particles - sc-63080-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU137231 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN20707 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND20707 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR12637 from Sigma-Aldrich
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STARD8 siRNA (Human) - CRH6520 from Cohesion Biosciences
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STARD8 - MBS8222438 from MyBioSource
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shRNA set against Human STARD8 (NM_014725.4) - SHH419360 from Creative biogene
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Human STARD8 siRNA - orb267022 from Biorbyt
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STARD8 shRNA Plasmid (Human) - CHH6520 from Cohesion Biosciences
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STARD8 miRNA 3'UTR clone - MiUTR3H-02903 from Creative biogene
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STARD8 miRNA 3'UTR clone - MiUTR3H-02904 from Creative biogene
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STARD8 miRNA 3'UTR clone - MiUTR3H-02905 from Creative biogene
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