Gene Symbol |
STARD8
|
Entrez Gene |
9754
|
Alt Symbol |
ARHGAP38, DLC3, STARTGAP3
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
StAR-related lipid transfer (START) domain containing 8
|
Other Description |
START domain containing 8|deleted in liver cancer 3 protein|stAR-related lipid transfer protein 8
|
Swissprots |
D3DVT9 A8K6T2 Q5JST0 Q68DG7 Q92502
|
Accessions |
EAX05374 EAX05375 Q92502 AK291747 BAF84436 BC035587 AAH35587 BQ019015 CR749411 CAH18253 D80011 BAA11506 DQ890917 ABM81843 XM_005262314 XP_005262371 XM_005262315 XP_005262372 XM_011531069 XP_011529371 XM_011531070 XP_011529372 NM_001142503 NP_001135975 NM_001142504 NP_001135976 NM_014725 NP_055540
|
Function |
Accelerates GTPase activity of RHOA and CDC42, but not RAC1. Stimulates the hydrolysis of phosphatidylinositol 4,5- bisphosphate by PLCD1. {ECO:0000269|PubMed:17976533}.
|
Subcellular Location |
Cell junction, focal adhesion {ECO:0000269|PubMed:17976533}.
|
Tissue Specificity |
Widely expressed with highest levels in kidney, lung and placenta. {ECO:0000269|PubMed:17297465}.
|